Papers - Okada, Yasunori
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Acute 40 percent exchange-transfusion with hemoglobin-vesicles (HbV) suspended in recombinant human serum albumin solution: degradation of HbV and erythropoiesis in a rat spleen for 2 weeks.
Sakai H, Horinouchi H, Yamamoto M, Ikeda E, Takeoka S, Takaori M, Tsuchida E, Kobayashi K:
Transfusion. 46 339-347, 2006
Research paper (scientific journal), Joint Work
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ADAM28 is overexpressed in human non-small cell lung carcinomas and correlates with cell proliferation and lymph node metastasis.
Ohtsuka T., Shiomi T., Shimoda M., Kodama T., Amour A., Murphy G., Ohuchi E., Kobayashi K. and Okada Y.:
Int. J. Cancer 118 263-273, 2006
Research paper (scientific journal), Joint Work
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Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis.
Komiya K., Enomoto H., Inoki I., Okazaki S., Fujita Y., Ikeda E., Ohuchi E., Matsumoto H., Toyama Y. and Okada Y.:
Arthritis Res. Ther. 7 R1158-R1173, 2005
Research paper (scientific journal), Joint Work
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deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice.
Matsumura S., Iwanaga S., Mochizuki S., Okamoto H., Ogawa S. and Okada Y.: Targeted
J. Clin. Invest. 115:599-609, 2005
Research paper (scientific journal), Joint Work
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Human glioblastomas overexpress ADAMTS-5 that degrades brevican.
Nakada M., Miyamori H., Kita D., Takahashi T., Yamashita J., Sato H., Miura R., Yamaguchi Y. and Okada Y.:
Acta Neuropathol. 110:239-246, 2005
Research paper (scientific journal), Joint Work
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Development of in situ zymography to selectively localize active matrix metalloproteinase (matrilysin-1).
Nemori R., Yamamoto M., Arakatsu H., Kataoka F., Hashimoto G., Shiomi T. and Okada Y.:
J. Histochem. Cytochem. 53 1227-1234, 2005
Research paper (scientific journal), Joint Work
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Pericellular activation of proMMP-7 (promatrilysin-1) through interaction with CD151.
Shiomi T., Inoki I., Kataoka F., Ohtsuka T., Hashimoto G., Nemori R. and Okada Y.:
Lab. Invest. 85 1489-1506, 2005
Research paper (scientific journal), Joint Work
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RAの滑膜病理
OKADA YASUNORI
内科診療Q&A 39 78-79 2004.12
Research paper (scientific journal), Single Work
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Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.
'Uekita T, Gotoh I, Kinoshita T, Itoh Y, Sato H, Shiomi T, Okada Y, Seiki M.'
Journal Biology Chemistry 279 ( 13 ) 12734-43. Epub 2004 Jan 12 2004.03
Research paper (scientific journal), Single Work
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Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the cupin superfamiily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.
'Uekita T., Gotoh I., Kinoshita T., Itoh Y., Sato H., Shiomi T., Okada Y. and Seiki M.:'
Journal Biology Chemistry 279 12734-12743 2004.03
Research paper (scientific journal), Single Work
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Constitutive and induced CD44 shedding by ADAM-like proteases and MT1-MMP: Shedding site-specific promotion of tumor cell invasion.
'Nakamura H., Suenaga N., Taniwaki, K., Matsuki H., Yonezawa, K., Fujii, M., Okada Y. and Seiki M.:'
Cancer Research 64 876-882 2004.02
Research paper (scientific journal), Single Work
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ADAM28 is activated by MMP-7 (matrilysin-1) and cleaves insulin-like growth factor binding protein-3.
'Mochizuki Satsuki, Shimoda Masayuki, Shiomi Takayuki, Fujii Y. and Okada Yasunori'
Biochemical Biophysical Research Communication 315 79-84 2004.01
Research paper (scientific journal), Single Work
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'Poellinger L., Okada Y., Morimoto C. and Tanaka H.: Hypoxia-inducible factor regulates survival of antigen receptor-driven T cells.'
'Makino Y., Nakamura H., Ikeda E., Ohnuma K., Yamauchi K., Yabe Y.,'
Journal Immunology 171 '6534-6540,' 2003.12
Research paper (scientific journal), Single Work
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Monoclonal antibodies with defined recognition sequences in the stem region of CD44: Detection of differential glycosylations of CD44 between tumor and stroma cells in tissue.
'Matsuki H., Yonezawa K., Obata K., Iwata K., Nakamura H., Okada Y. and Seiki M.'
Cancer Research 63 8278-8283 2003.12
Research paper (scientific journal), Single Work
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Qualitative analysis of circulating and tissue forms of gelatinase A (MMP-2) and B (MMP-9) in colon carcinomas by mono- and two-dimensional gelatin zymography
Pucci-Minafra Ida, Minafra Salvatore, La Rocca, Giampiero, Barranca Marilisa, Fontana Simona, Alaimo Giuseppina, Okada Yasunori
Matrix biology 20 ( 7 ) 419-427 2003.11
Research paper (scientific journal), Joint Work
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: Detection of von Willebrand factor-cleaving protease (ADAMTS-13) in human platelets.
'Suzuki M., Murata M., Matsubara Y., Uchida T., Ishihara H., Shibano T., Ashida S., Soejima K., Okada Yasunori. Ikeda Yasuo'
BiochemicalBiophysical Research Communnication 313 212-216 2003.11
Research paper (scientific journal), Single Work
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ADAM
岡田愛子、 岡田保典
臨床整形外科 0 ( 0 ) 2003.11
Research paper (scientific journal), Single Work
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肺の組織構築改変。
潮見隆之、 岡田保典
病理と臨床 21 1219-1224 2003.11
Research paper (scientific journal), Single Work
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マトリックスメタロプロテアーゼと癌転移。
潮見隆之、 岡田保典
現代医療 35 2967-2973 2003.11
Research paper (scientific journal), Single Work
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浸潤性胸腺腫・重症筋無力症の経過観察中に巨細胞性心筋炎・筋炎を併発した１例。
佐藤秀樹、岩崎栄典、野川 茂、鈴木重明、天野隆弘、福内靖男、下田将之、岡田保典
臨床神経学 43 496-499 2003.08
Research paper (scientific journal), Single Work
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Role of Crk-associated lymphocyte type in the pathophysiology of rheumatoid arthritis in tax transgenic mice and in humans.
'Miyake-Nishijima R., Iwata S., Saijo S., Kobayashi H., Kobayashi S., Souta-Kuribara A., Hosono O., Kawasaki H., Tanaka H., Ikeda E., Okada Y., Iwakura Y. and Morimoto C.'
Arthritis Rheumatology 48 1890-1900 2003.07
Research paper (scientific journal), Single Work
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Invasive lobular carcinoma arising in phyllodes tumor of the breast.
'Kodama Takayuki, Kameyama Kaori, Mukai Makio, Ikeda T. Okada Yasunori'
Virchows Archiv 442 '614-616,' 2003.06
Research paper (scientific journal), Single Work
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Cleavage of Metastasis Suppressor Gene Product KiSS-1 Protein/Metastin by Matrix Metalloproteinases.
'Takino, T., Koshikawa, N., Miyamori, H., Tanaka, M., Sasaki, T., Okada, Y., Seiki, M., and Sato. H.:'
Oncogene 22 4617-4626 2003.06
Research paper (scientific journal), Single Work
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Reduced angiogenesis in peritoneal dissemination of gastric cancer through gelatinase inhibition.
'Wada N, Otani Y, Kubota T, Kimata M, Minagawa A, Yoshimizu N, Kameyama K., Saikawa Y., Yoshida M., Furukawa T., Fujii M, Kumai K, Okada Y, Kitajima Masaki'
Clinical Experimental Metastasis 20 '20: 431-435,' 2003.05
Research paper (scientific journal), Single Work
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Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy. Invest
'Noda Kousuke, Ishida Susumu, Inoue M, Obata K, Oguchi Y, Okada Yasunori, Ikeda Eiji'
Ophthalmology Vis. Science 44 2163-2170 2003.05
Research paper (scientific journal), Single Work
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MT1-MMP and MMP-7 in invasion and metastasis of human cancers.
'Shiomi Takayuki, Okada Yasunori'
Cancer Metastasis Review 22 145-152 2003.05
Research paper (scientific journal), Single Work
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A case of sclerosing hemangioma of the lung presenting as a gigantic tumor occupying thoracic cavity.
'Shibata R., Mukai M., Okada Y., Yamauchi T. and Kobayashi K.:'
Virchows Archiv 442 409-411 2003.05
Research paper (scientific journal), Single Work
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MMPと骨吸収
小宮 浩一郎、 岡田 保典
骨・関節疾患 p58-p64 2003.04
Research paper (scientific journal), Single Work
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The role of matrix metalloproteinases in glioma invasion. Recent Advances in Neuro-Oncology
Nakada Mitsutoshi, Okada Yasunori, Yamashita Junkoh
Frontiers in bioscience 8 261-269 2003.01
Research paper (scientific journal), Joint Work
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Vascular endotherial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage
Enomoto Hiroyuki, Inoki Isao, Komiya Koichiro, Shiomi Takayuki, Ikeda Eiji, Obata Ken-ichi, Matsumoto Hideo, Toyama Yoshiaki, Okada Yasunori
American journal pathology 162 ( 1 ) 171-181 2003.01
Research paper (scientific journal), Joint Work
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Emphysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1
Shiomi Takayuki, Okada Yasunori, Foronjy Robert, Schilts John, Jaenish Rudolph, Krane Steve, D'Armiento Jeanine
Experimental lung research 29 ( 1 ) 39097 2003.01
Research paper (scientific journal), Joint Work
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Vascular endotherial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage
Enomoto Hiroyuki, Inoki Isao, Komiya Koichiro, Shiomi Takayuki, Ikeda Eiji, Obata Kenichiro, Matsumoto Hideo, Toyama Yoshiaki, Okada Yasunori
American journal of pathogy 162 171-181 2003
Research paper (scientific journal), Joint Work
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The role of matrix metalloproteinases in glioma invasion. Frontiers in Bioscience
Nakada Mitsutoshi, Okada Yasunori
Recent advances in neuro-oncology 2003
Research paper (scientific journal), Joint Work
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細胞外マトリックス代謝の病理
Okada Yasunori
日本病院会雑誌 91 61-79 2002.12
Research paper (scientific journal), Single Work
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蛋白分解酵素
Okada Yasunori
リウマチ基本テキスト 89-95 2002.12
Research paper (scientific journal), Single Work
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Satellite lesions in patientswith small hepatocellular carcinoma with reference to clinicopathologic features
Okusaka Takuji, Okada Shuichi, Ueno Hideki, Ikeda Masafumi Shimada Kazuaki, Yamamoto Junji, Kosuge Tomoo, Yamazaki Susumu, Fukushima Noriyuki, Sakamoto Michiie
Cancer 95 ( 9 ) 1931-1937 2002.11
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase inhibitor, Marimastat, decreases peritoneal spread of gastric carcinoma in nude mice
Kimata Masaru, Otani Yoshihide, Kubota Tetsuro, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norihito, Yoshimizu Nobunari, Kameyama Kaori, Okada Yasunori, Kumai Koichiro, Kitajima Masaki
Japanese journal of cancer research 93 834-841 2002.10
Research paper (scientific journal), Joint Work
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RGD-CAP (big-h3) is expressed in precartilage condensation and in prehypertrophic chondrocytes during cartilage development
Ohno S, Doi T, Tsutsumi S, Okada Yasunori, Yoneno K, Kato Y, Tane K
Biochimica. biophysica. acta 1572 ( 1 ) 114-122 2002.08
Research paper (scientific journal), Joint Work
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Matrix Metalloproteinase Inhibitor, Marimastat, Decreases Peritoneal Spread of Gastric Carcinoma in Nude Mice
Kimata Masaru, Otani Yoshihide, Kubota Tetsuro, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norito, Yoshimizu Nobunari, Fujii Masato, Kameyama Kaori, Okada Yasunori, Kumai Koichiro, Kitajima Masaki
Japanese journal of cancer research 93 834-841 2002.07
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase inhibitor, marimastat, decreased peritoneal spread of gastric carcinoma in nude mice
Kimata Masaru, Otani Yoshihide, Kubota Tetsuro, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norihito, Yoshimizu Nobunari, Fujii Masato, Kameyama Kaori, Okada Yasunori, Kumai Koichiro, Kitajima Masaki
Japanese journal of cancer research 93 ( 7 ) 834-841 2002.07
Research paper (scientific journal), Joint Work
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MT1-MMP and MMP-7 in invasion and metastasis of human cancers
Shiomi Takayuki, Okada Yasunori
Cancer metastasis review 22 ( 2-3 ) 145-152 2002.06
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase inhibitor, marimastat, decrease peritoneal spread of gastric carcinoma in nude mice
Kimata Masaru, Otani Yoshihide, Kubota Tetsuo, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norihiro, Yoshimizu Nobunari, Fujii Masato, Kameyama Kaori, Okada Yasunori, Kumai Koichiro, Kitajima Masaki
Japanese journal of cancer research 93 ( 6 ) 834-841 2002.06
Research paper (scientific journal), Joint Work
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Neuromuscular and vasculara hamartoma f cecum
Shiomi T, Kameyama K, Kawano Y, Shimizu Y, Takabayashi T, Okada Y
Virchrows Archiv 440 ( 3 ) 338-340 2002.03
Research paper (scientific journal), Joint Work
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Reduced levels of MMP-2 and TIMP-1 in dyssegmental dysplasia
Uchide K, Ueno H, Takizawa N, Okada Yasunori
Journal of bone mineral research 18 ( 2 ) 381 2002.02
Research paper (scientific journal), Joint Work
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MMP/TIMPカスケード
Matsumura Shinichirou, Okada Yasunori
現代医療 35 319-324 2002.02
Research paper (scientific journal), Joint Work
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Connective tissue growth factor binds vascular endotheloal growth factor(VEGF)and inhibits VEGF-induced angiogenesis
Inoki I, Shiomi T, Hashimoto G, Enomoto H, Nakamura H, Makino K, Ikeda E, Takata S, Kobayashi K, Okada Y
The FASEB Journal 16 ( 2 ) 219-221 2002.02
Research paper (scientific journal), Joint Work
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Vascular Endothelial Growth Factor Isoforms and their receptors are expressed in human osteoarthritic cartilage
Enomoto Hiroyuki, Inoki Isao, Komiya Koichiro, Shiomi Takayuki, Ikeda Eiji, Obata Ken-ichi, Matsumoto Hideo, Toyama Yoshiaki, Okada Yasunori
American journal of pathology 161 ( 1 ) 171-181 2002.01
Research paper (scientific journal), Joint Work
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関節軟骨細胞外マトリックスの分解とMMP/ADAMS
Komiya Kouichirou，Okada Yasunori
Molecular Medicine 39 40-47 2002.01
Research paper (scientific journal), Joint Work
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Empysematous changes are caused by degradation of type III collagen in transgenic mice expressing MMP-1
Shiomi Takayuki, Okada Yasunori, Foronjy R, Schiltz J, Jaenish R, Krane S, D/Armiento J
Experimental lung research 29 ( 1 ) 1-15 2002.01
Research paper (scientific journal), Joint Work
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Two-step sandwich enzyme immunoassay using monoblonal antibodies for detection of soluble and menbrane-associated human membrane type 1-matrix metalloproteinase
Aoki T，Yonezawa K，Ohuchi E，Fujimoto N，Iwata K，Shimada K，Shiomi T，Okada Y，Seiki M
Journal of Immunoassay & Immunochemistry 23 ( 1 ) 49-68 2002.01
Research paper (scientific journal), Joint Work
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プロテアーゼ：多彩な機能と疾患への関与(オーバービュー)
Okada Yasunori
Molecular Medicine 39 4-8 2002.01
Research paper (scientific journal), Single Work
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Two-step sandwich enzyme immunoassay using monoclonal antibodies for detection of soluble and membrane-associated human membrane type 1-matrix metalloproteinase
Aoki T, Okada Yasunori,
Journal Immunoassay Immunochemistry 23 ( 1 ) 49-68 2002
Research paper (scientific journal), Joint Work
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The citrus flavonoid, nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice
Minagawa A, Otani Y, Kubota T, Wada N, Furukawa T, Kumai K, Kameyama K, Okada Y, Fujii M, Yano M, Sato T, Ito A, Kitajima M
Japanese Journal of Cancer Research 92 ( 12 ) 1322-1328 2001.12
Research paper (scientific journal), Joint Work
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The citrus flavonoid, Nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice
Minagawa Akiko, Otani Yoshihide, Kubota Tetsuo, Wada Norihito, Furukawa Toshiharu, Kumai Koichiro, Kameyama Kaori, Okada Yasunori, Fujii Masato, Yano Masamichi, Sato Takashi, Ito Akira, Kitajima Masaki
Japanese Journal of Cancer Research 92 ( 12 ) 1322-1328 2001.12
Research paper (scientific journal), Joint Work
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The citrus flavonoid, nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice
Minagawa Akiko, Otani Yoshihide, Kubota Teturo, Wada Norihito, Furukawa Toshiharu, Kumai Koichirou, Kameyama, Kaori, Okada Yasunori, Fujii Masato, Yano Masamichi, Sato Takashi, Ito Akira, Kitajima Masaki
Japanese Journal of Cancer Research 92 ( 12 ) 1322-1328 2001.12
Research paper (scientific journal), Joint Work
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The citrus flavonoid, nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice
Minagawa Akiko, Otani Yoshihide, Kubota Tetsuro, Wada Norihito, Furukawa Toshiharu, Kumai Koichirou, Kameyama, Kaori, Okada Yasunori, Fujii Masato, Yano Masamichi, Sato Takashi, Ito Akira, Kitajima Masaki
Japanese Journal of Cancer Research 92 ( 12 ) 1322-1328 2001.12
Research paper (scientific journal), Joint Work
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The citrus flavonoid nobiletin inhibits peritoneal dissemination of human gastric carcinoma in SCIDmice
Minagawa A, Otani Y, Kubota T, Wada N, Furukawa T, Kumai K, Kameyama K, Okada Y, Fujii M, Yano M, Sato T, Ito A, Kitajima M
Japanese Journal of Cancer Research 92 ( 12 ) 1322-1328 2001.12
Research paper (scientific journal), Joint Work
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マトリックスメタプロテアーゼによる細胞外マトリックス代謝と関節破壊
Okada Yasunori，Hashimoto Gakuji
生化学 73 1309-1321 2001.11
Research paper (scientific journal), Joint Work
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実験的肺気腫モデル
Imai Kazushi，Sanada Kazuo，Okada Yasunori
The Lung 9 270-274 2001.09
Research paper (scientific journal), Joint Work
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骨吸収とMMP/ADAM
Enomoto Hiroyuki，Okada Yasunori
医学のあゆみ 198 580-584 2001.09
Research paper (scientific journal), Joint Work
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Clinical role of Tc-99m-MIBI scintigraphy in non-Hodgkin's lymphoma
Ohta M, Isobe K, Kuyama J, Uchida Y, Nakao K, Goto S, Uno T, Yasuda S, Shigematsu N, Kawata A, Kitahara H, Ito H
Oncology Reports 8 ( 4 ) 841-845 2001.07
Research paper (scientific journal), Joint Work
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ApoE knock-out mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis
Lemaitre V, O'Byrne T.K, Borczuk A.C, Okada Y, Tall A.R, D'Armiento J
The Journal of Clinical Investigation 107 ( 10 ) 1227-1234 2001.05
Research paper (scientific journal), Joint Work
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Inhibition of ADAMTS4 (arrecaanase-1)by tissue inhibitors of metalloproteinases(TIMP-1,2,3and4)
Hashimoto G, Aoki T, Nakamura H, Tanzawa K, Okada Y
FEBS Letters 494 ( 3 ) 192-195 2001.05
Research paper (scientific journal), Joint Work
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MMPとTIMP
Nakamura Hiroyuki，Okada Yasunori
Vascular Biologyナビゲーター 214-215 2001.04
Research paper (scientific journal), Joint Work
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慢性関節リウマチとMMPS
Enomoto Hiroyuki，Okada Yasunori
The bone 15 ( 2 ) 53-58 2001.03
Research paper (scientific journal), Joint Work
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慢性関節リウマチ
Ikeda Eiji，Okada Yasunori
現代医療 33 ( 1 ) 115-121 2001.01
Research paper (scientific journal), Joint Work
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慢性関節リウマチ
Ikeda Eiji，Okada Yasunori
現代医療 33 ( 1 ) 115-121 2001
Research paper (scientific journal), Joint Work
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関節軟骨とMMP
Okazaki Satoko，Okada Yasunori
現代医療 133 ( 5 ) 49-55 2001
Research paper (scientific journal), Joint Work
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One-step sandwich enzyme immunoassay using monoclonal antibodies for detection of human enamelysis(MMP-20)
Wang T, Aoki T, Iwata K, Takata T, Uchida T, Knauper V, Llano E, Okada Y, Barlett JD
European Journal of Oral Sciences 108 ( 6 ) 530-537 2000.12
Research paper (scientific journal), Joint Work
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Brevican is degraded by matrix metalloproteinases(MMPs) and aggrecanase-1(ADAMTS4) at the different sites
Nakamura H, Fujii Y, Inoki I, Sugimoto K, Tanzawa T, Matsuki H, Miura R, Yamaguchi Y, Okada Y
Journal of Biological Chemistry 275 ( 49 ) 38885-38890 2000.12
Research paper (scientific journal), Joint Work
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Tumor cell-matrix interaction:Pericellular matrix degradation and metastasis
Okada Y
Verhandlungen der Deutscheu Gesellschaft fur Pathologie 84 33-42 2000.12
Research paper (scientific journal), Single Work
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Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human oral squamous cell carcinomas:implications for lymph node metastasis
Shimada T, Nakamura H, Yamashita K, Kawata R, Murakami Y, Fujimoto N, Sato H, Seiki M, Okada Y
Clinical & Experimental Metastasis 18 ( 2 ) 179-188 2000.12
Research paper (scientific journal), Joint Work
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慢性関節リウマチの発症病理─炎症から骨破壊へ─病理学的立場から
Okada Yasunori
日本内科学会雑誌 89 ( 10 ) 2072-2080 2000.10
Research paper (scientific journal), Single Work
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ADMTS-1 cleaves a cartilage proteoglycan, aggrecan
Kuno K, Okada Y, Kawashima H, Nakamura H, Miyasaka M, Ohno H, Matsushima K
FEBS Letters 478 ( 3 ) 241-245 2000.10
Research paper (scientific journal), Joint Work
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Expression of emmprin(CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas
Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S
International Journal of Cancer 88 ( 1 ) 21-27 2000.10
Research paper (scientific journal), Joint Work
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腫瘍の浸潤・転移とMMP
Okada Yasunori
産科と婦人科 67 ( 9 ) 1115-1124 2000.09
Research paper (scientific journal), Single Work
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Matric -degrading metalloproteinases and their roles in joint destruction
Okada Y
Mod.Rheumatol 10 ( 3 ) 121-128 2000.09
Research paper (scientific journal), Single Work
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MMPs/TIMPsのカスケード:マトリックス研究のニューウエーブ
Nakamura Hiroyuki，Okada Yasunori
最新医学 58 ( 8 ) 1751-1758 2000.08
Research paper (scientific journal), Joint Work
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Expression of vascular endothelial growth factor isoforms and their receptors Flt-1, KDR ,and neuropilin-1 in synovial tissue of rheumatoid arthritis
Ikeda M, Hosoda Y, Hirose S, Okada Y, Ikeda E
Journal of Pathology 191 ( 4 ) 426-433 2000.08
Research paper (scientific journal), Joint Work
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Glioma cell extracellular matrix metalloproteinases inducer (EMMPRIN)(CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelantinase A in co-cultures with brain-derived fibroblasts
Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S
Cancer Letters 157 ( 2 ) 177-184 2000.08
Research paper (scientific journal), Joint Work
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Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and glatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor
Nabeshima K, Inoue T, Shimao Y, Okada Y, Itoh Y, Seiki M, Koono M
Cancer Research 60 ( 13 ) 3364-3369 2000.07
Research paper (scientific journal), Joint Work
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Matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in fetal rabbit lung
Fukuda Y, Ishizaki M, Okada Y, Seiki M, Yamanaka N
American Journal of Physiology. Lung Cellular and Molecular Physiology. 279 ( 3 ) L555-L561 2000.07
Research paper (scientific journal), Joint Work
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Matrix metalloproteinases and tissue inhibitor of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis
Yoshihara Y, Nakamura H, Obata K, Yamada H, Hayakawa T, Fujikawa K, Okada Y
Annals of the Rheumatic Diseases 59 ( 6 ) 455-461 2000.07
Research paper (scientific journal), Joint Work
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Matrix metalloproteinases-9 and tensile strength in fetal membranes with uncomplicated labor
Uchide K, Ueno H, Inoue M, Sakai A, Fujimoto N, Okada Y
Obstetrics and Gynecology 95 ( 6pt1 ) 851-855 2000.06
Research paper (scientific journal), Joint Work
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Co-expression of VEGF receptors VEGF-R2 and neuropilin-1 proliferative diabetic retinopathy
Ishida S, Shinoda K, Kawashima S, Oguchi Y, Okada Y, Ikeda E
Investigative Ophtalmology & Visual Science 41 ( 7 ) 1649-1656 2000.06
Research paper (scientific journal), Joint Work
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Expression and tissue localization of menbrane-type 1,2 and 3 matrix metalloproteinases in rheumatoid arthitis
Yamanaka H, Makino K, Takizawa M, Nakamura H, Fujimoto N, Moriya H, Nemori R, Sato H, Seiki M, Okada Y
Laboratory Investigation 80 ( 5 ) 677-687 2000.05
Research paper (scientific journal), Joint Work
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慢性関節リウマチとMMP
Yoshihara，Fujigawa Kyousuke
現代医療 32 ( 4 ) 969-976 2000.04
Research paper (scientific journal), Joint Work
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オーバービュー：MMPの疾患とのかかわり
Okada Yasunori
現代医療 32 ( 4 ) 962-967 2000.04
Research paper (scientific journal), Single Work
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癌の浸潤・転移とMMP
Nakamura Hiroyuki，Okada Yasunori
現代医療 32 ( 4 ) 991-997 2000.04
Research paper (scientific journal), Joint Work
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Modulation of collagen synthesis by tumor necrosis factor alpha in cultured smooth muscle cells
Hiraga Syouichi, Kaji Toshiyuki, Ueda Yoshimichi, Zisaki Fumihko, Iwata Kazushi, Koizumi Fumitomo, Okada Yasunori, Katsuda Shogo, Nakanishi Isao
Life Sciences 66 ( 3 ) 235-244 2000.03
Research paper (scientific journal), Joint Work
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Production of tissue inhibitor of metalloproteinases-3 is selectively enhanced by calcium pentosan polysulfate in human rheumatoid synovial fibroblasts
Takizawa M, Ohuchi E, Yamanaka H, Nakamura H, Ikeda E, Ghosh P, Okada Y
Arthritis and Rheumatism 43 ( 4 ) 812-820 2000.03
Research paper (scientific journal), Joint Work
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Marked increase of matrix netalloproteinase 9 in cerebrospinal fluid of patients with fungal or tuberculosis meningoencephalitis
Matsuura Eiji, Uehara Fujio, Hashiguchi Teruo, Fujimoto Noboru, Okada Yasunori, Osame Mitsuhiro
Journal of The Neurological Sciences 173 ( 1 ) 45-52 2000.01
Research paper (scientific journal), Joint Work
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マトリックスメタロプロテアーゼ（MMP）研究の最近の進展─MMPとADAMによる細胞外マトリックス代謝─
Okada Yasunori
医学のあゆみ 191 ( 12+13 ) 1108 1999.12
Research paper (scientific journal), Single Work
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ヌードマウス胃癌腹膜播種モデルにおけるマトリックス分解酵素阻害剤TA2516（Marimastat）の腫瘍抑制効果
Kimata Masaru, Otani Yoshihide, Kubota Tetsuro, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norihito, Okada Yasunori, Kameyama Kaori, Kitajima Masaki
日本外科学会雑誌 100 363-363 1999.11
Research paper (scientific journal), Joint Work
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消化器癌転移抑制におけるMMP活性阻害の意義
Ootani Yoshihide, Kimata Dai, Igarashi Naoki, Kubota Tetsurou, Kitajima Masaki, Fujii Masato, Kameyama Kaori, Okada Yasunori
Biotherapy 13 679-685 1999.10
Research paper (scientific journal), Joint Work
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マトリックスメタロプロテアーゼ研究の現状と展望─特集に寄せて─
Okada Yasunori
組織培養工学 25 ( 9 ) 334-335 1999.09
Research paper (scientific journal), Single Work
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Shedding of membrane typr matricx metalloproteinase in a human breast carcinoma cell line
Harayama Takeshi, Ohuchi Eiko, Aoki Takanori, Sati Hiroshi, Seiki Motoharu, Okada Yasunori
Japanese Journal of Cancer Research 90 ( 9 ) 942-950 1999.09
Research paper (scientific journal), Joint Work
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Shedding of membrane typr matricx metalloproteinase in a human breast carcinoma cell line
Harayama Takeshi, Ohuchi Eiko, Aoki Takanori, Sati Hiroshi, Seiki Motoharu, Okada Yasunori
Japanese Journal of Cancer Research 90 ( 9 ) 942-950 1999.09
Research paper (scientific journal), Joint Work
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Enhanced production and activation of matrix metalloproteinase-7 (matrilysin) in human endometrial carcinomas.
Ueno Hirohisa, Yamashita Kaname, Azumano Isao, Inoue Masaki, Okada Yasunori
International Journal of Cancer 84 ( 5 ) 470-477 1999.09
Research paper (scientific journal), Joint Work
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Contribution of matrilysin (MMP-7) to metastatic pathway of human colorectal cancers.
Adachi Yasushi, Yamamoto Hiroyuki, Itoh Fumio, Hinoda Yuji, Okada Yasunori, Imai Kouzo
Gut 45 ( 2 ) 252-258 1999.08
Research paper (scientific journal), Joint Work
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Expression of matrix metalloproteinases in gastric carcinoma and possibility of clinical application of matrix metalloproteinase ihibitor in vivo In: Inhibition and Matrix Metalloproteinases.
Otani Yoshihide, Kubita Tetsuro, Sakurai Yoshihiko, Igarashi Naoki, Yokoyama Takeyoshi, Kimata Masaru, Wada Norihiko, Kameyama Kaori, Kumai Koichiro, Okada Yasunori, Kitajima Masaki
Annals of the New York Academy of Sciences 878 541-543 1999.08
Research paper (scientific journal), Joint Work
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プロテアーゼによる慢性関節リウマチ関節軟骨破壊
Okada Yasunori
病理と臨床 17 ( 7 ) 711-717 1999.07
Research paper (scientific journal), Single Work
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Expression of matrix metalloproteinases in gastric carcinoma and possibility of clinical application of matrix metalloproteinase inhibitor in vivo
Otani Y, Kubota T, Sakurai Y, Igarashi N, Yokoyama T, Kimata M, Wada N, Kameyama K, Kumai K, Okada Y, Kitajima M
New York Academy of Science 878 541-543 1999.07
Research paper (scientific journal), Joint Work
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慢性関節リウマチ滑膜におけrく血管新生因子
Ikeda Eiji, Okada Yasunori
病理と臨床 17 ( 7 ) 706-710 1999.07
Research paper (scientific journal), Joint Work
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細胞外マトリックス分解による関節軟骨破壊
Enomoto Hiroyuki, Okada Yasunori
Rheumatol. Clin. Update 2 38-39 1999.07
Research paper (scientific journal), Joint Work
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characterization of a truncated recombinant form of human membrane type 3 matrix metalloproteinase
Shimada Taketoshi, Nakamura Hiroyuki, Ohuchi Eiko, Fujii Yutaka, Murakami Yasushi, Sato Hiroshi, Seiki Motoharu, Okada Yasunori
European Journal of Biochemistry 262 ( 3 ) 907-914 1999.06
Research paper (scientific journal), Joint Work
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消化器癌転移抑制におけるMMP活性阻害の意義
Ootani Yoshihide, Kimata Masaru, Igarashi Naoki, Kubota Tetsurou, Kitajima Masaki, Fujii Masahito, Kameyama Kaori, Okada Yasunori
Biotherapy 13 ( 6 ) 679-685 1999.06
Research paper (scientific journal), Joint Work
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消化器癌転移抑制におけるMMP活性阻害の意義─臨床応用への展望─
Ootani Yoshihide, Kimata Dai, Igarashi Naoki, Kubota Tetsurou, Kitajima Masaki, Fujii Masato, Kameyama Kaori, Okada Yasunori
Biotherapy 13 ( 6 ) 679-685 1999.06
Research paper (scientific journal), Joint Work
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消化器癌転移抑制におけるMMP活性阻害の意義─臨床応用への展望
Otani Yoshihide, Kimata Masaru, Igarashi Naoki, Kubota Tetsuro, Kitajima Masaki, Fujii Masato, Kameyama Kaori, Okada Yasunori
Biotherapy 13 ( 6 ) 679-685 1999.06
Research paper (scientific journal), Joint Work
-
ヌードマウス胃癌腹膜播種モデルにおけるマトリックス分解酵素阻害剤TA-2516（Marimastat）の腫瘍抑制効果
Kimata Masaru, Ootani Yoshihide, Kubota Tetsurou, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norihito, Kumai Kouichirou, Okada Yasunori, Kameyama Kaori, Kitajima Masaki
日本外科学会雑誌 100 ( 5 ) 363 1999.05
Research paper (scientific journal), Joint Work
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ヌードマウス胃癌腹膜播モデルにおけるマトリックス分解酵素阻害剤TA-2516（Marimastat）の腫瘍抑制効果
Kimata Masaru, Ootani Yoshihide, Kubota Tetsurou, Igarashi Naoki, Yokoyama Takeyoshi, Wada Norihito, Kumai Kouichirou, Okada Yasunori, Kameyama Kaori, Kitajima Masaki
日本外科学会雑誌 100 ( 5 ) 363 1999.05
Research paper (scientific journal), Joint Work
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細胞膜貫通型メタロプロテアーゼと骨・軟骨破壊
Takizawa Masayuki, Okada Yasunori
炎症と免疫 7 ( 3 ) 263-270 1999.04
Research paper (scientific journal), Joint Work
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Ets-1 positively regulates expression of urokinase type plasminogen activator (uPA) and invasiveness of astrocytic tumors.
Nakada Mitsutoshi, Yamashita Junko, Okada Yasunori, Sato Hiroshi
Jouranl of Neuropathology and Experimental Neurology 58 ( 4 ) 329-334 1999.04
Research paper (scientific journal), Joint Work
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組織破壊性プロテアーゼとしてのマトリックスメタロプロテアーゼ
Nakada Mitsutoshi, Okada Yasunori
呼吸 18 ( 4 ) 365-371 1999.04
Research paper (scientific journal), Joint Work
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慢性関節リウマチの関節軟骨破壊
Okada Yasunori
病理と臨床 17 ( 臨増 ) 298 1999.04
Research paper (scientific journal), Single Work
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関節炎，関節症の分子病理
Nakamura Hiroyuki, Okada Yasunori
MB Orthop 12 10-17 1999.03
Research paper (scientific journal), Joint Work
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Expression and tissue locali of membrane-types 1,2,3 matrix metalloproteinases in human astrocytic tumors
Nakada Mitsutoshi, Nakamura Hiroyuki, Ikeda Eiji, Fujimoto Noboru, Yamashita Junkoh, Sato Hiroshi, Seiki Motoharu, Okada Yasunori
American Journal of Pathology 154 ( 2 ) 417-428 1999.02
Research paper (scientific journal), Joint Work
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Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinoms
Nakamura Hiroyuki, Ueno Hirohisa, Yamashita Kaname, Shimada Takatoshi, Yamamoto Etsuhide, Noguchi Masakuni, Fujimoto Noboru, Sato Hiroshi, Seiki Motoharu, Okada Yasunori
Cancer Research 59 ( 2 ) 467-473 1999.01
Research paper (scientific journal), Joint Work
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消化器癌転移抑制におけるMMP活性阻害の意義─臨床応用への展望
Otani Yoshihide, Kimata Masaru, Igarashi Naoki, Kubota Tetsuro, Kitajima Masaki, Fujii Masato, Kameyama Kaori, Okada Yasunori
Biotherapy 13 ( 6 ) 679-685 1999
Research paper (scientific journal), Joint Work
-
ヌードマウス胃癌腹膜播種モデルにおけるマトリックス分解酵素阻害剤TA-2516（Marimastat）の腫瘍抑制効果
木全大，大谷吉秀，久保田哲朗，五十嵐直喜，横山剛義，和田則仁，熊井浩一郎，岡田保典，亀山香織，北島政樹
日外会誌 100 ( 5 ) 363 1999
Research paper (scientific journal), Joint Work
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Expression of matrix metalloproteinases in gastric carcinoma and possibility of clinical application of matrix metalloproteinase inhibitor in vivo
Otani Yoshihide, Kubota Tetsuro, Sakurai Yoshihiko, Igarashi Naoki, Yokoyama Takeyoshi, Kimata Masaru, Wada Norihito, Kameyama Kaori, Kumai Koichiro, Okada Yasunori, Kitajima Masaki
Annals of the New York Academy of Sciences 878 541-543 1999
Research paper (scientific journal), Joint Work
-
消化器癌転移抑制におけるMMP活性阻害の意義─臨床応用への展望
Otani Yoshihide, Kimata Masaru, Igarashi Naoki, Kubota Tetsuro, Kitajima Masaki, Fujii Masato, Kameyama Kaori, Okada Yasunori
Biotherapy 13 ( 6 ) 679-685 1999
Research paper (scientific journal), Joint Work
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MMP研究の動向
Okada Yasunori
リウマチ科 20 527-534 1998.12
Research paper (scientific journal), Single Work
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Expression of membrane-bound transferrin-like protein p97 on the cell surface of chondrocytes
Kawamoto Takeshi, Pan Haiou, Yan Weiqun, Ishida Hideyuki, Usui Emiko, Oda Ryo, Nakamasu Kazuko, Noshiro Mitsuhide, Kawashima-oyha Yoshie, Fujii Masashi, Shintani Hideaki, Okada Yasunori, Kato Yukio
European Journal of Biochemistry 256 503-509 1998.12
Research paper (scientific journal), Joint Work
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Expression of telomerase activity in human endometrium is localized to epithelial proliferation
Tanaka Masaaki, Kyo Satoru, Takakura Masahiro, Kanaya Taro, Sagawa Tetsuya, Yamashita Kaname, Okada Yasunori, Hiyama Eiso, Inoue Masaki
American Journal of Pathology 153 ( 6 ) 1985-1991 1998.12
Research paper (scientific journal), Joint Work
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MMPと腫瘍形成，転移
Shimada Taketoshi, Okada Yasunori
実験医学 16 138-143 1998.10
Research paper (scientific journal), Joint Work
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Expression and tissue localization of membrane-types 1,2 and 3 matrix metalloproteinases in human urothelial carcinomas
Kitagawa Yasuhide, Kunimi Kazuto, Ito Hideaki, Sato Hiroshi, Uchibayashi Tadao, Okada Yasunori, Seiki Motoharu, Namiki Mikio
Journal of Urology 160 ( 4 ) 1540-1545 1998.10
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase
Okada Yasunori
整形外科 49 1364 1998.10
Research paper (scientific journal), Single Work
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Small solid renal lesions: Usefulness of power doppler US
Jinzaki M, Ohkuma K, Tanimoto A, Mukai M, Hiramatsu K, Murai M, Hata J
Radiology 209 543-550 1998.09
Research paper (scientific journal), Joint Work
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Membrane-type 1 MMP(MMP-14)cleaves at three sites in the aggrecan interglobular domain
Fosang Amanda J, Last Karena, Fujii Yutaka, Seiki Motoharu, Okada Yasunori
FEBS Letters 430 186-190 1998.07
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase(MMP)の研究および臨床の現状
Otani Yoshihide, Fujii Masato, Kubota Tetsuro, Kitajima Masaki, Okada Yasunori
癌と化学療法 25 957-964 1998.07
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase(MMP)の研究および臨床の現状
Otani Yoshihide, Fujii Masato, Kubota Tetsuro, Kitajima Masaki, Okada Yasunori
癌と化学療法 25 957-964 1998.07
Research paper (scientific journal), Joint Work
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TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads
Kinoshita Takeshi, Sato Hiroshi, Okada Akiko, Ohuchi Eiko, Imai Kazuki, Okada Yasunori, Seiki Motoharu
Journal of Biological Chemistry 273 ( 26 ) 16098-16103 1998.06
Research paper (scientific journal), Joint Work
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Matrix metalloproteinase (MMP)の研究および臨床の現状
Ootani Yoshihide, Fujii Masato, Kubota Tetsurou, Kitajima Masaki, Okada Yasunori
癌と化学療法 25 ( 6 ) 957-964 1998.06
Research paper (scientific journal), Joint Work
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Matrix Metalloproteinase(MMP)の研究及び臨床の現状
Ootani Yoshihide, Fujii Masato, Kubota Tetsurou, Kitajima Masaki, Okada Yasunori
癌と化学療法 25 ( 7 ) 957-964 1998.06
Research paper (scientific journal), Joint Work
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Inhibition of membrane-type 1 marix metalloproteinase by hydroxamate inhibitors: An examination of the subsite pocket
Yamamoto Minoru, Tsujishita Hideki, Hori Noriyuki, Ohishi Yuichi, Inoue Shintaro, Ikeda Shoji, Okada Yasunori
Journal of Medical Chemistry 41 ( 8 ) 1209-1217 1998.04
Research paper (scientific journal), Joint Work
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細胞外基質を構成する分子のがん組織における特徴
Ootani Yoshihide, Okada Yasunori
細胞工学 17 ( 4 ) 514-522 1998.04
Research paper (scientific journal), Joint Work
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Activation of the precursor of human stromelysin 2 and its interactions with other matrix metalloproteinases
Nakamura Hiroyuki, Fuji Yutaka, Ohuchi Eiko, Yamamoto Etuhide, Okada Yasunori
European Journal of Biochemistry 253 ( 2 ) 67-75 1998.04
Research paper (scientific journal), Joint Work
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Effects of parathyroid hormone and its related peptide on matrix metalloproteinases-2, -3 and -9 syntheses by growth plate chondrocytes
Kawashima-Ohya Y, Satakeda H, Kuruta Y, Kawamoto T, Yan W, Akagawa Y, Hayakawa T, Noshiro M, Okada Y, Nakamura S, Kato Y
Endocrinology 139 2120-2127 1998.03
Research paper (scientific journal), Joint Work
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A one-step monoclonal antibody-based sandwich enzyme immunoassay for human active matrilysin (MMP-7) and its complexes with TIMP-1 and TIMP-2
Azumano I, Fujimoto N, Teshima M, Yoshida S, Iwata K, Okada Y
Connective Tissue 30 23-28 1998.03
Research paper (scientific journal), Joint Work
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Expression of matrix metalloproteinase 7 (matrilysin) in human osteoarthritic cartilage
Ohta S, Imai K, Yamashita K, Matsumoto T, Azumano I, Okada Y
Lab Invest 78 79-87 1998.01
Research paper (scientific journal), Joint Work
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細胞外基質を構成する分子のがん組織における特徴
Otani Yoshihide, Okada Yasunori
細胞工学 17 514-522 1998.01
Research paper (scientific journal), Joint Work
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Molecular analysis of new cases of Japanese patients of holocarboxylase synthetase deficiency
Sakamoto O, Suzuki Y, Aoki Y, Li X, Hiratsuka M, Yanagihara K, Inui K, Okabe T, Yamaguchi S, Kudoh J, Shimizu S, Narisawa K
Journal of Inherited Metabolic Disease 21 ( 8 ) 873-874 1998
Research paper (scientific journal), Joint Work
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Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion
Sato H, Okada Y, Seiki M
Thromb Haemost 78 497-500 1997.11
Research paper (scientific journal), Joint Work
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人工関節looseningの機構
Yokohama Yasuo, Okada Yasunori
骨・関節・靱帯 10 735-742 1997.09
Research paper (scientific journal), Joint Work
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消化器とECM代謝
Imai Kazushi, Okada Yasunori
G. I. Research 5 135-142 1997.09
Research paper (scientific journal), Joint Work
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プロテアーゼと炎症
Oouchi Eiko, Okada Yasunori
現代医療 29 2315-2321 1997.09
Research paper (scientific journal), Joint Work
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膜結合型メタロプロテアーゼとマトリックス代謝
Ueno Hirohisa, Okada Yasunori
生体の科学 48 301-306 1997.08
Research paper (scientific journal), Joint Work
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Complement Cls, a classical enzyme with novel functions at endochondral ossification center : Immunohistochemical staining of activated Cls with a neoantigen specific antibody
Sakiyama H, Nakagawa K, Kuriiwa K, Imai K, Okada Y, Tsuchida T, Moriya H, Imajoh-Ohmi S
Cell Tissue Res 288 557-565 1997.08
Research paper (scientific journal), Joint Work
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関節軟骨の破壊と細胞外マトリックス分解酵素
Imai Kazushi, Okada Yasunori
医学のあゆみ 182 549-553 1997.08
Research paper (scientific journal), Joint Work
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Enhancement of cartilage matrix protein synthesis in arthritic cartilage
Okimura A, Okada Y, Makihira S, Pan H, Yu L, Tanne K, Imai K, Yamada H, Kawamoto T, Noshiro M, Yan W, Kato Y
Arthritis Rheum 40 1029-1036 1997.07
Research paper (scientific journal), Joint Work
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Expression of membrane-type 1 Matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage
Imai K, Ohta S, Matsumoto T, Fujimoto N, Sato H, Seiki M, Okada Y
Am J Pathol 151 245-256 1997.07
Research paper (scientific journal), Joint Work
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MMPs(matrix metalloproteinases)
Okada Yasunori
医学のあゆみ 181 653-654 1997.05
Research paper (scientific journal), Single Work
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Expression and tissue localization of membrane-type 1, 2 and 3 matrix metalloproteinases in human invasive breast carcinomas
Ueno H, Nakamura H, Inoue M, Imai K, Noguchi M, Sato H, Seiki M, Okada Y
Cancer Res 57 2055-2060 1997.05
Research paper (scientific journal), Joint Work
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Degradation of decorin by matrix metalloproteinases. Identification of the cleavage sites, kinetic analysis and transforming growth factor-β1 release
Imai K, Hiramatsu A, Fukushima D, Pierschbacher MD, Okada Y
Biochem J 322 809-814 1997.04
Research paper (scientific journal), Joint Work