KEIO RESEARCHERS INFORMATION SYSTEM

Academic Degrees 【 Display / hide 】

Academic Degrees 【 Display / hide 】

• Doctor of Philosophy in Medicine（PhD in Medicine）, Keio University, National Institution for Academic Degrees and University Evaluation, 2023.03

• Master of Science in Nursing（MSN）, Keio University, National Institution for Academic Degrees and University Evaluation, 2008.03

Licenses and Qualifications 【 Display / hide 】

Licenses and Qualifications 【 Display / hide 】

• Registered Nurse, 2001.04

• Certified Nurse Specialist in Psychiatric Mental Health Nursing, 2009.12

• Certified Public Psychologist, 2021.12

Papers 【 Display / hide 】

Papers 【 Display / hide 】

• Nurses’ and pharmacists’ perceptions of psychotropic medications used for delirium: A questionnaire survey.

  河野 佐代子, 清宮 啓介, 竹内 啓善

  臨床精神薬理 (星和書店)  29 ( 2 ) 217 - 228 2026.02

  Joint Work, Lead author, Accepted,  ISSN  1343-3474

• Effects of Intravenous Hydroxyzine Versus Haloperidol Monotherapy for Delirium: A Retrospective Study

  Kubo K., Takehara M., Hirata M., Huh S., Kawano S., Uchida H., Takeuchi H.

  Journal of Clinical Psychiatry 86 ( 1 )  2025.03

  ISSN  01606689

  　View Summary

  Objective: Although antipsychotics are used commonly for delirium, they increase the risk of mortality in elderly patients and those with dementia. As hydroxyzine has sedative and anxiolytic effects, it can be used in the treatment of delirium. We performed a retrospective study to compare the effects of intravenous hydroxyzine and haloperidol monotherapy on delirium. Methods: Patients who admitted to a university hospital from April 1, 2017, to September 30, 2022, and received either hydroxyzine or haloperidol intravenously as monotherapy for the treatment of delirium were included. The time to and rate of delirium improvement were compared. Improvement of delirium was defined as negative on the Confusion Assessment Method (CAM) or Confusion Assessment Method for the ICU (CAM-ICU) for 3 consecutive days. Results: Among 5,555 patients who developed delirium, 71 (1.3%) and 82 (1.5%) received intravenous hydroxyzine and haloperidol monotherapy, respectively. The time to delirium improvement was 7.0 days (95% CI, 5.7–8.3 days) for hydroxyzine and 8.2 days (95% CI, 7.6–8.8 days) for haloperidol, with no significant difference between the two groups (P= .059). On the other hand, the rate of delirium improvement was 23.9% for hydroxyzine and 8.5% for haloperidol, with a significant difference in favor of the hydroxyzine group (P = .009). Conclusions: We first showed that intravenous hydroxyzine monotherapy was not inferior for the time to delirium improvement and superior for the rate of delirium improvement to intravenous haloperidol monotherapy. Considering that hydroxyzine is relatively safe with few side effects, it can be a viable option for delirium as an alternative to antipsychotics.

  • Access to Document (DOI)

• Establishment and clinical impacts of decision-support system for older patients with aortic valve stenosis: A retrospective observational study

  Kawano S., Eguchi Y., Oosumi A., Takeuchi H., Takubo M., Kimura N., Nakano N., Ryuzaki T., Hayashida K., Ieda M., Uchida H., Mimura M., Fujisawa D.

  General Hospital Psychiatry 92   106 - 111 2025.01

  ISSN  01638343

  　View Summary

  Objectives: Treatment decisions for severe aortic stenosis (AS) are complex, since there are two active and comparable options: transcatheter aortic valve implantation and surgical aortic valve replacement. The disease predominantly affects older individuals, who are frequently comorbid with from cognitive impairment. This study aimed to establish a screening-triggered system to assess the decision-making capacity of patients with AS, support their decision-making, and facilitate referrals to specialists when necessary. Methods: This is a retrospective pre-post observational study. Relevant healthcare professionals were trained to assess and support patients' decision-making capacities. Results: Subtotals of 203 and 244 patients were enrolled before and after the implementation of the system, respectively. The requests for decision-making support significantly increased (from 1.5 % to 14.8 % of the patients). 11.5 % of the patients were identified as with declined decision-making capacity. The proportion of patients who received active treatments for AS significantly decreased from 95.0 % to 83.0 %. The nurses' documentation of patients' decision-making capacities significantly increased. Conclusion: This screening-triggered system identified a substantial proportion of patients with declined decision-making capacity. A significant decrease in patients receiving active treatments for AS and increased documentation of patients' decision-making capacities in nursing records were observed. A future randomized controlled is warranted.

  • Access to Document (DOI)

• Trazodone and Mianserin for Delirium: A Retrospective Chart Review

  Kawano S., Ide K., Kodama K., Kikuchi Y., Sugihara H., Fujisawa D., Uchida H., Mimura M., Takeuchi H.

  Journal of Clinical Psychopharmacology 42 ( 6 ) 560 - 564 2022.11

  ISSN  02710749

  　View Summary

  Background Although antipsychotics are commonly used for delirium, their adverse effects are a serious concern in light of extrapyramidal symptoms and cardiovascular disturbances. In clinical practice, sedative antidepressants are frequently used as an alternative treatment for delirium; however, there is scarce evidence. Thus, we conducted a retrospective chart review to examine the use and effectiveness of trazodone and mianserin for delirium. Methods Patients who were admitted to a university hospital during 4 years and received either trazodone or mianserin on a regular schedule as monotherapy for the treatment of delirium were included. The rates of and times to the improvement of delirium were compared. Results Among 3971 patients who developed delirium, 379 (9.5%) and 341 (8.6%) patients received trazodone and mianserin on a regular schedule; 52 and 46 patients met the eligibility criteria (ie, monotherapy) for trazodone and mianserin, respectively. The percentages of patients 65 years or older were 86.5% (n=45) for trazodone and 89.1% (n=41) for mianserin. The rates of the improvement of delirium were 63.5% for trazodone and 50.0% for mianserin. Times to the improvement of delirium were 5.3 days (95% confidence interval, 3.2-7.4 days) for trazodone and 9.3 days (95% confidence interval, 5.3-13.3 days) for mianserin. There were no significant differences in the primary outcomes between the 2 groups (P=0.17 and P=0.13, respectively). Conclusion Considering potentially serious, sometimes lethal, adverse effects of antipsychotics, sedative antidepressants such as trazodone and mianserin may be a treatment option for delirium, especially in the elderly.

  • Access to Document (DOI)

Reviews, Commentaries, etc. 【 Display / hide 】

Reviews, Commentaries, etc. 【 Display / hide 】

• 【終末期の身の置き所のなさとせん妄(terminal restlessness/agitation)の緩和ケア】身の置き所のなさと過活動型せん妄に対するケア　終末期せん妄でみられる身の置き所のなさへのケア

  河野佐代子

  緩和ケア (青海社)  33 ( 3 ) 229 - 234 2024.05

  Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media), Single Work, Lead author

• 【組織で取り組むメンタルサポート　慢性ストレスにさらされるスタッフを支え,バーンアウトや離職を防ぐ】実践報告　慶應義塾大学病院の取り組み　COVID-19という危機的な出来事に対して精神看護専門看護師だからこそできること

  河野佐代子

  看護管理 (医学書院)  31 ( 11 ) 996 - 1001 2021.11

  Lead author,  ISSN  0917-1355

• 【ICTが徹底的に確認すべし!新型コロナウイルス対策最重要チェックポイント】医療従事者の心をケアする

  河野佐代子

  INFECTION CONTROL (メディカ出版)  30 ( 6 ) 591 - 596 2021.06

  Lead author

• 看護スタッフのCOVID-19関連ストレスのメンタルサポート　現場の看護管理者が考えるべきこと・すべきこと(後編)

  武用 百子, 寺岡 征太郎, 岩切 真砂子, 蒲池 あずさ, 河野 伸子, 河野 佐代子, 菊池 美智子, 曽根原 純子

  ナースマネージャー (日総研)  22 ( 6 ) 88 - 94 2020.08

• 【プライマリ・ケア医が知っておくべき心不全診療】治療　非薬物治療　高齢者のSHDカテーテル治療の適応

  竜崎 俊亘, 河野 佐代子, 江口 洋子, 林田 健太郎

  治療 (南山堂)  102 ( 6 ) 728 - 732 2020.06

  Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)

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Presentations 【 Display / hide 】

Presentations 【 Display / hide 】

• 多職種チームによる高齢者意思決定支援の定着に向けた実践プロセス

  河野 佐代子, 江口 洋子, 大角 梓, 藤澤 大介, 田久保 美千代, 木村 範子, 中野 直美, 田中 謙二, 内田 裕之, 竹内 啓善, 林田 健太郎, 竜崎 俊宣, 坂田 新悟, 三村 將

  [Domestic presentation]  老年精神医学会, 

  2021.11

  -

  2022.11

  , 

  Poster presentation

• 精神看護専門看護師を中心とする精神科エゾチームの役割と課題

  KANNO SAYOKO

  [Domestic presentation]  第27回　日本総合病院精神医学会 (茨城県) , 

  2014.11

• 新人看護師のストレス状況とメンタルヘルスに関する一考察

  KANNO SAYOKO

  [Domestic presentation]  第21回精神保健看護学会 (愛知県産業労働センター（ウインクあいち）) , 

  2011.06

  , 

  Oral presentation (general)

Courses Taught 【 Display / hide 】

Courses Taught 【 Display / hide 】

• PRACTICUM IN PSYCHIATRIC AND MENTAL HEALTH CARE

  2026

• PSYCHIATRIC AND MENTAL HEALTH NURSING

  2026

• SEMINAR IN PSYCHIATRIC AND MENTAL HEALTH NURSING INTERVENTIONS

  2026

• SEMINAR IN PSYCHIATRIC AND MENTAL HEALTH NURSING

  2026

• PSYCHIATRIC AND MENTAL HEALTH NURSING

  2019