Papers - Yamada, Toru

Lewis Acid-catalyzed Decarboxylative Cyanation of Cyclic Enol Carbonates ®Access to Multi-substituted ¢-Ketonitriles®

Yokoyama H., Dokai Y., Kimaru N., Saito K., Yamada T.

Chemistry Letters (Chemistry Letters)  51 ( 4 ) 469 - 472 2022.04

Joint Work,  ISSN  03667022

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A Lewis acid-catalyzed decarboxylative substitution reaction of cyclic enol carbonates with a cyanation reagent was developed to give ¢-ketonitriles in good yield. It is proposed that the reaction proceeds through an oxyallyl cation intermediate or its equivalent. Interestingly, cyanation selectively took place at the more hindered site of the intermediate to afford a multi-substituted ¢-ketonitrile. This regioselectivity was observed by the cyanation of a wide range of substrates and is discussed in terms of the reaction mechanism.

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Microwave-specific enhancement of nazarov cyclization

Kubota Y., Kawanori T., Sawada T., Saito K., Yamada T.

Chemistry Letters (Chemistry Letters)  50 ( 1 ) 144 - 146 2021.01

Research paper (scientific journal), Joint Work, Accepted,  ISSN  03667022

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A copper-catalyzed Nazarov cyclization was carried out under conventional heating conditions and microwave conditions. Under strictly temperature-controlled conditions, the use of microwave irradiation improved the chemical yields. Consequently, the kinetic rate of the microwave irradiation was 5.8 times higher than that of the conventional heating conditions. These observations suggested that the microwave specific effects enhanced the efficiency of the Nazarov reaction.

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Stereoselective amination: Via vinyl-silver intermediates derived from silver-catalyzed carboxylative cyclization of propargylamine

Sadamitsu Y., Saito K., Yamada T.

Chemical Communications (Chemical Communications)  56 ( 66 ) 9517 - 9520 2020.08

ISSN  13597345

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© The Royal Society of Chemistry. The stereoselective synthesis of aminovinyloxazolidinones based on the electrophilic amination of a vinyl-silver intermediate, generated by silver-catalyzed carbon dioxide incorporation on a propargyl amine, was achieved. The geometry of the aminated product was determined by a single crystal X-ray analysis and NOE measurement and it was elucidated that the geometry was proved to be opposite to the geometry predicted from the previous silver-catalyzed carbon dioxide fixation on a propargyl amine derivative. This unexpected stereoselectivity could be successfully explained by a radical mechanism. This journal is

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Thermal decarboxylative Nazarov cyclization of cyclic enol carbonates involving chirality transfer

Kozuma A., Komatsuki K., Saito K., Yamada T.

Chemistry Letters (Chemistry Letters)  49 ( 1 ) 60 - 63 2020

Research paper (scientific journal), Joint Work, Accepted,  ISSN  03667022

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© 2020 The Chemical Society of Japan. Decarboxylative Nazarov cyclization of chiral cyclic enol carbonates proceeded to afford chiral 2-cyclopentenones with excellent chirality transfer under thermal conditions without any catalyst. Interestingly, the thermal decarboxylative Nazarov cyclization furnished the desired product with better chirality transfer than the Lewis acid-catalyzed reaction.

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Silver-Catalyzed Carbon Dioxide Fixation on Alkynylindenes

Okumura A., Chuang P.Y., Saito K., Yamada T.

Organic Letters (Organic Letters)   2020

ISSN  15237060

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© The synthesis of polycyclic indene derivatives via silver-catalyzed carbon dioxide fixation on 2-alkynylindene derivatives was achieved by nucleophilic addition of the indenyl anion to carbon dioxide involving carbon-carbon bond formation and subsequent intramolecular cyclization to the alkyne part activated by a silver catalyst. This cascade process could be applied to various substrates to obtain the corresponding products in high yields. The endo/exo selectivity of the cyclization could be controlled by the steric or electronic effect of the substituents on the substrates, and 6-endo-selective cyclization was realized to afford α-pyrone-fused indenes.

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Decarboxylative Nazarov Cyclization-Based Chirality Transfer for Asymmetric Synthesis of 2-Cyclopentenones

Komatsuki K., Kozuma A., Saito K., Yamada T.

Organic Letters (Organic Letters)  21 ( 17 ) 6628 - 6632 2019.09

ISSN  15237060

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© 2019 American Chemical Society. Asymmetric synthesis of 2-cyclopentenones was achieved by chirality transfer based on Lewis acid catalyzed decarboxylative Nazarov cyclization of optically active cyclic enol carbonates, which are prepared by silver-catalyzed carbon dioxide incorporation into optically pure propargyl alcohols. The stereochemistry at the 4,5-positions of the 2-cyclopentenones was cleanly constructed by reflecting the stereochemistry of the starting materials. This method could be applied to various substrates to obtain the corresponding products in high yields with highly efficient chirality transfer.

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Microwave specific effect on catalytic enantioselective reactions

Yamada T.

Asia-Pacific Microwave Conference Proceedings, APMC (Asia-Pacific Microwave Conference Proceedings, APMC)  2018-November   1627 - 1629 2019.01

Research paper (scientific journal), Joint Work, Accepted,  ISSN  9784902339451

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© 2018 IEICE The microwave specific effect was investigated on the catalytic enantioselective reactions; atropo-enantiveselective ring-opening reaction of biaryl lactones and enantioselective Claisen rearrangement reaction. These reactions were efficiently enhanced with microwave irradiation under reaction temperature control, thought any loss of the enantioselectivities were not detected. It was also found that the racemization rate of the atropo-optically active biaryl lactone was enhanced by microwave irradiation. As these observations could not be explained by the simple thermal effect, microwave specific effect should be considered.

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Kolbe-Schmitt type reaction under ambient conditions mediated by an organic base

Sadamitsu Y., Okumura A., Saito K., Yamada T.

Chemical Communications (Chemical Communications)  55 ( 66 ) 9837 - 9840 2019

ISSN  13597345

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© 2019 The Royal Society of Chemistry. The combined use of an organic base for resorcinols realized a Kolbe-Schmitt type reaction under ambient conditions. When resorcinols (3-hydroxyphenol derivatives) were treated with DBU under a carbon dioxide atmosphere, nucleophilic addition to carbon dioxide proceeded to afford the corresponding salicylic acid derivatives in high yields.

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7 Silver-Catalyzed CO2 Incorporation

Yamada T., Sekine K., Sadamitsu Y., Saito K.

Silver Catalysis in Organic Synthesis (Silver Catalysis in Organic Synthesis)     407 - 438 2018.12

Research paper (scientific journal), Joint Work, Accepted,  ISSN  9783527342815

Amidation reaction of carboxylic acid with formamide derivative using SO<inf>3</inf>•pyridine

Kawano S., Saito K., Yamada T.

Chemistry Letters (Chemistry Letters)  47 ( 4 ) 584 - 586 2018

Research paper (scientific journal), Joint Work, Accepted,  ISSN  03667022

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© 2018 The Chemical Society of Japan. The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3•py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.

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Microwave-Specific Effect on Enantioselective Reactions

YAMADA TOHRU

Journal of the Jpn. Petrol. Inst. (石油学会)  61 ( 2 ) 121 - 128 2018

Research paper (scientific journal), Joint Work, Accepted,  ISSN  13468804

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© 2018 Office of the Federal Register. All rights reserved. Microwave irradiation is widely applied to organic synthesis. Many advantages of microwave irradiation, including drastic shortening of reaction time, suppression of side reactions, and/or higher chemical yield, have been proposed. Generally, these effects have been understood merely as a simple thermal effect, since microwave irradiation rapidly raises the temperature of the reaction mixture. However, some observed results could not be understood only by the thermal effect. Recently our group reported that several enantioselective reactions were accelerated under microwave irradiation without loss of enantioselectivity. As these extraordinary results could not be explained by the simple thermal effect, the concept of the "microwave-specific effect" should be considered. We describe our recent experimental results to elucidate the microwave-specific effect. Investigations are described on enantioselective ring-opening reactions of biaryl lactone derivatives, racemization of an optically pure biaryl lactone derivative, enantioselective Claisen rearrangement reaction, enantioselective Conia-ene reaction and ring-closing metathesis reaction. These reactions or racemization of optically pure compounds were accelerated under microwave conditions. Such reaction acceleration of enantioselective reactions was observed without loss of enantioselectivity.

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Amidation Reaction of Carboxylic Acid with Formamide Derivative Using SO3·pyridine

YAMADA TOHRU

Chem. Lett. (日本化学会)  47   584 - 586 2018

Research paper (scientific journal), Joint Work, Accepted

Stereospecific Decarboxylative Nazarov Cyclization Mediated by Carbon Dioxide for the Preparation of Highly Substituted 2-Cyclopentenones

YAMADA TOHRU

Angew. Chem. Int. Ed. (Wiley)  56   11594 - 11598 2017

Research paper (scientific journal), Joint Work, Accepted

Microwave Enhancement on Ring-closing Metathesis of Macrocyclic Bisazole

YAMADA TOHRU

Chem. Lett. 46   274 - 276 2017

Research paper (scientific journal), Joint Work, Accepted

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Access to Tetronic Acids via a Silver-Catalyzed CO2 Incorporation Reaction into Conjugated Ynones

YAMADA TOHRU

Org. Lett. (ACS)  19   3191 - 3194 2017

Research paper (scientific journal), Joint Work, Accepted

Silver-catalyzed Three-component Reaction of Propargylic Amines, Carbon Dioxide, and N-Bromosuccinimide for Stereoselective Preparation of (E)-Bromovinyloxazolidinones

YAMADA TOHRU

Chem. Lett. (日本化学会)  46   1323 - 1326 2017

Research paper (scientific journal), Joint Work, Accepted

Silver-Catalyzed Carboxylation,

YAMADA TOHRU

Chemical Society Reviews 45   4524 - 4532 2016

Accepted

Microwave Specific Effect on Catalytic Enantioselective Conia-Ene Reaction

YAMADA TOHRU

Chem. Lett. 45   649 - 651 2016

Accepted

Microwave Specific Effect on Catalytic atropo-Enantioselective Ring-Opening Reaction of Biaryl Lactones

YAMADA TOHRU

Bull. Chem. Soc. Jon. 89   833 - 835 2016

Accepted

Silver-catalyzed Cascade Carboxylation and Cyclization of Trimethyl(2-methylenebut-3-yn-1-yl)silane Derivatives

YAMADA TOHRU

Org. Lett. 17   5706 - 5709 2015

Accepted

Enantioselective Michael Addition Catalyzed by the Optically Active 1-Chlorovinyl Cobalt(III) Complex

YAMADA TOHRU

Synlett 26   1111 - 1115 2015

Joint Work, Accepted

Cobalt-Catalyzed Reductive Carboxylation on αβ-Unsaturated Compounds with Carbon Dioxide

YAMADA TOHRU

Bull. Chem. Soc. Jpn. 88   862 - 870 2015

Research paper (scientific journal), Joint Work, Accepted

Silver-Catalyzed Three-Component Reaction of Propargylic Amines, Carbon Dioxide and N-Iodosuccinimide for Stereoselective Preparation of (E)-Iodovinyl Oxazolidinones

YAMADA TOHRU

Chem. Lett. 44   1407 - 1409 2015

Accepted

Tandem Cyclization of Propargylic Alcohols and Phenyl Isocyanate for 2-Oxazolidinones promoted by Silver Catalysts as π–Lewis Acid

YAMADA TOHRU

Synlett 26   2447 - 2450 2015

Accepted

Carbon Dioxide Incorporation into Alkylenic Compounds Mediated by Silver Catalyst

S. Kikuchi and T. Yamada,

The Chemical Record 14   62 - 69 2014

Research paper (scientific journal), Accepted

Cobalt-Catalyzed Reductive Carboxylation on α,β-Unsaturated Nitriles with Carbon Dioxide

C. Hayashi, T. Hayashi, S. Kikuchi and T. Yamada

Chem./ Lett. 43   565 - 567 2014

Research paper (scientific journal), Joint Work, Accepted

Silver-catalyzed Efficient Synthesis of Vinylene Carbonate Derivatives from Carbon Dioxide

R. Ugajin, S. Kikuchi, T. Yamada

Synlett 25   1178 - 1180 2014

Research paper (scientific journal), Joint Work, Accepted

Novel Method of Tetramic Acid Synthesis: Silver-Catalyzed Carbon Dioxide Incorporation into Propargylic Amine and Intramolecular Rearrangement

T. Ishida, R. Kobayashi,T. Yamada

Org. Lett. 16   2430 - 2433 2014

Research paper (scientific journal), Joint Work, Accepted

Silver-catalyzed Efficient Synthesis of Vinylene Carbonate Derivatives from Carbon Dioxide

YAMADA TOHRU

Synlett 25   1178 - 1180 2014

Research paper (scientific journal), Joint Work, Accepted

Cobalt-Catalyzed Reductive Carboxylation on α,β-Unsaturated Nitriles with Carbon Dioxide

YAMADA TOHRU

Chem. Lett. 43   565 - 567 2014

Joint Work, Accepted

Silver-Catalyzed C-C Bond Formation with Carbon Dioxide: Significant Synthesis of Dihydroisobenzofurans

K. Sekine, A. Takayanagi, S. Kikuchi, T. Yamada

Chem. Commun. 49   11320 - 11322 2013

Research paper (scientific journal), Joint Work, Accepted

Silver-Catalyzed Incorporation of Carbon Dioxide into o-Alkynylaniline Derivatives

YAMADA TOHRU

Org. Lett. 15   848-851 2013

Research paper (scientific journal), Joint Work, Accepted

Extraordinary Microwave Effect on atropo-EnantioselectiveCatalytic Reduction of Biaryl Lactones

YAMADA TOHRU

Chem. Lett 42   165-167 2013

Research paper (scientific journal), Single Work, Accepted

Reusable Cobalt(III) Complex Catalysts for Enantioselective Borohydride Reduction of Ketones

T. Tsubo, H.-H. Chen, M. Yokomori, S. Kikuchi, and T. Yamada

Bull. Chem. Soc. Jpn. 86   983 - 986 2013

Research paper (scientific journal), Joint Work, Accepted

Microwave Effect on Catalytic Enantioselective Claisen Rearrangement

K. Nushiro, S. Kikuchi, and T. Yamada

Chem. Comm. 49   8371 - 8373 2013

Research paper (scientific journal), Joint Work, Accepted

Efficient Preparation of 4-Hydroxyquinolin-2(1H)-one Derivatives with Silver-Catalyzed Carbon Dioxide Incorporation and Intramolecular Rearrangement

T. Ishida, S. Kikuchi, and T. Yamada

Org. Lett. 15   3710 - 3713 2013

Research paper (scientific journal), Joint Work

Structure Determination of the Cobalt(III) Complex Catalyst for Enantioselective Borohydride Reduction

YAMADA TOHRU

Chem. Lett 41   783-785 2012

Research paper (scientific journal), Single Work, Accepted

Enantioselective Borohydride Reduction of Aliphatic Ketones Catalyzed by Ketoiminatocobalt(III) Complex with 1-Chlorovinyl Axial Ligand

YAMADA TOHRU

Chem. Lett 41   780-782 2012

Research paper (scientific journal), Single Work, Accepted

Homogeneous Enantioselective Catalysis in a Continuous-Flow Microreactor: Highly Enantioselective Borohydride Reduction of Ketones Catalyzed by Optically Active Cobalt Complexes

YAMADA TOHRU

Organic Process Research & Development 16   1235−1240 2012

Research paper (scientific journal), Single Work, Accepted

Catalytic C-C Bond Formation with Carbon Dioxide by Silver Catalyst

YAMADA TOHRU

Angew. Chem. Int. Ed 51   6989-6992 2012

Research paper (scientific journal), Single Work, Accepted

Alternating Copolymerization of Propylene Oxide / Alkylene Oxide and Carbon Dioxide: Tuning Thermal Properties of Polycarbonates

YAMADA TOHRU

Chem. Lett. 40   209-211 2011

Research paper (scientific journal), Single Work, Accepted

Silver-Catalyzed Carbon Dioxide Incorporation and Rearrangement Reaction on Propargylic Derivatives

YAMADA TOHRU

Bull. Chem. Soc. Jpn. 84   698-717 2011

Research paper (scientific journal), Single Work, Accepted

New Class of Catalyst for Alternating Copolymerization of Alkylene Oxide and Carbon Dioxide

YAMADA TOHRU

Chem. Lett 39   1066-1068 2010

Research paper (scientific journal), Joint Work, Accepted

Extraordinary Effect of Microwave Irradiation on Asymmetric Catalysis

YAMADA TOHRU

Chem. Lett. 39   574-575 2010

Research paper (scientific journal), Joint Work, Accepted

Silver-Catalyzed Enantioselective Carbon Dioxide Incorporation into Bispropargylic Alcohols

YAMADA TOHRU

J. Am. Chem. Soc. 132   4072-4073 2010

Research paper (scientific journal), Joint Work, Accepted

Cobalt-catalyzed Oxidative Kinetic Resolution of Secondary Benzylic Alcohols with Molecular Oxygen

YAMADA TOHRU

Chem. Lett. 38   40-41 2009

Research paper (scientific journal), Joint Work, Accepted

Silver-catalyzed Preparation of Oxazolidinones from Carbon Dioxide and Propargylic Amines

YAMADA TOHRU

Chem. Lett. 38   786-787 2009

Research paper (scientific journal), Joint Work, Accepted

Stereo- and Regioselectivity in an Intramolecular Nitrone-Alkene Cycloaddition of Hept-6-enones with a trans-Acetonide Blocking Group

YAMADA TOHRU

Chem. Eur. J. 15   2693-2707 2009

Research paper (scientific journal), Joint Work, Accepted

Catalytic atropo-Enantioselective Preparation of Axially Chiral Biary Compounds

YAMADA TOHRU

Chem. Lett. 38   246-247 2009

Research paper (scientific journal), Joint Work, Accepted

Catalytic Atropo-Enantioselective Reaction of Biaryl Lactones into Axially Chiral Biaryl Compounds

YAMADA TOHRU

Org. Lett. 10   2521-2524 2008

Research paper (scientific journal), Joint Work, Accepted

Carbon Dioxide-Mediated Catalytic Rearrangement of Propargyl Alcohols into α,β-Unsaturated Ketones

YAMADA TOHRU

J. Am. Chem. Soc. 129   12902-12903 2007

Research paper (scientific journal), Joint Work, Accepted

Stereoselective Preparation of α-Hydroxycarboxamide by Manganese Complex Catalyzed Hydration of α,β-Unsaturated Carboxamide with Molecular Oxygen and Phenylsilane

YAMADA TOHRU

Chemistry Letters 33 ( 10 ) 1304-1305 2004.10

Research paper (scientific journal), Single Work

Nitrous Oxide Oxidation Catalyzed by Ruthenium Porphyrin Complex

YAMADA TOHRU

Bull. Chem. Soc. Jpn 77 ( 10 ) 0905-1914 2004.10

Research paper (scientific journal), Single Work

FT-IR and Theoretical Analysis of the Characteristic Bonding Properties in the Multiplet Metal Porphyrin Carbene Complexes

YAMADA TOHRU

Chem. Lett. 33   140-141 2004

Research paper (scientific journal), Joint Work, Accepted

[N,N’-Bis(2-methoxycarbonyl-3-oxobutylidene)-ethylenediaminato-k4O,N,N’,O’]cobalt(II)

YAMADA TOHRU

Acta Crystallographica Section E 60   m149-m150 2004

Research paper (scientific journal), Joint Work, Accepted

Proposal for the Metallacycle Pathway during the Cyclopropanation Catalyzed by Cobalt-Schiff Base Complexes

YAMADA TOHRU

Org. Lett. 6   949-952 2004

Research paper (scientific journal), Joint Work, Accepted

Enantioselective Henry Reaction Catalyzed by Optically Active Ketoiminatocobalt Complexes

YAMADA TOHRU

Chem. Lett. 33 ( 5 ) 614-615 2004

Research paper (scientific journal), Joint Work, Accepted

Enantioselective CO2 Fixation Catalyzed by Optically Active Cobalt Complexes

YAMADA TOHRU

Chem. Lett. 33 ( 6 ) 676-677 2004

Research paper (scientific journal), Joint Work, Accepted

Efficient Preparation of Optically Pure C2-Symmetrical Cyclic Amines for Chiral Auxiliary

YAMADA TOHRU

Synthesis 2004 ( 9 ) 1434-1438 2004

Research paper (scientific journal), Joint Work, Accepted

Enantioselective Henry Reaction Catalyzed by Salen Cobalt Complexes

YAMADA TOHRU

Synthesis 2004 ( 12 ) 1947-1950 2004

Research paper (scientific journal), Single Work

Enantioselective Carbonyl-Ene Reaction of Glyoxal Derivatives Catalyzed by Cationic 3-Oxobutylideneaminatocobalt (III) Complexes

YAMADA TOHRU

Bull. Chem. Soc. Jpn. 76   49-58 2003.01

Research paper (scientific journal), Joint Work, Accepted

光学活性ケトイミナトコバルト錯体触媒による不斉ボロヒドリド還元反応

YAMADA TOHRU

有機合成化学協会誌 61 ( 9 ) 843-856 2003

Research paper (scientific journal), Joint Work

Catalytic Enantioselective Protonation of Cobalt-enolate Equivalent Generated by Borohydride 1,4-Reduction

YAMADA TOHRU

Tetrahedron: Asymmetry 14   967-970 2003

Research paper (scientific journal), Joint Work, Accepted

Efficient Oxidative Aromatization of 9,10-Dihydroanthracenes with Molecular Oxygen Catalyzed by Ruthenium Porphyrin Complex

YAMADA TOHRU

Synlett 2003   576-578 2003

Research paper (scientific journal), Joint Work, Accepted

Enantioselective Borohydride Reduction Catalyzed by Optically Active Cobalt Complexes

YAMADA TOHRU

Chem. Eur. J. 9   4485-4509 2003

Research paper (scientific journal), Joint Work, Accepted

Enantioselective 1,3-Dipolar Cycloaddition Reactions between Nitrones and a-Substituted a,b-Unsaturated Aldehydes Catalyzed by Chiral Cationic Co(III) Complexes

YAMADA TOHRU

Synthesis 2003   1462-1466 2003

Research paper (scientific journal), Joint Work, Accepted

Preparation of optically active deuterated primary alcohols: Enantioselective borodeuteride reduction of aldehydes catalyzed by cobalt complexes

YAMADA TOHRU

New J. Chem. 27   1164-1166 2003

Research paper (scientific journal), Joint Work, Accepted

Enantioselective 1,3-Dipolar Cycloaddition Reaction of Nitrones with a,b-Unsaturated Aldehydes Catalyzed by Cationic 3-Oxobutylideneaminatocobalt(III) Complexes

YAMADA TOHRU

Bull. Chem. Soc. Jpn. 76   2197-2207 2003

Research paper (scientific journal), Joint Work, Accepted

Synthesis of Polyphenylene Ether Derivatives: Estimation of Their Dielectric Constants

YAMADA TOHRU

Macromol. Chem. Phys. 204   1876-1881 2003

Research paper (scientific journal), Joint Work, Accepted

Enantioselective Borodeuteride Reduction of Aldimines Catalyzed by Cobalt Complexes: Preparation of Optically Active Deuterated Primary Amines

YAMADA TOHRU

Org. Lett. 5   3555-3558 2003

Research paper (scientific journal), Joint Work, Accepted

Theoretical Analysis of the Reaction Pathway and the Effect of the Axial Ligand for the 3-Oxobutylideneaminatocobalt(II) Complex Catalyzed Cyclopropanation

池野　健人・岩倉　いずみ・薮下　聡・山田　徹

Org. Lett. Vol.4   517-521 2002.02

Research paper (scientific journal), Joint Work

Dynamic Kinetic Resolution with Enantioselective Borohydride Reduction Catalyzed by Optically Active β-Ketoiminato Cobalt(II) Complexes: Highly Diastereo- and Enantioselective Preparation of Optically Active anti-Aldol Compounds

大塚　雄紀・宮崎　大地・池野　健人・山田　徹

Chem. Lett. 2002   24-25 2002.01

Research paper (scientific journal), Joint Work

Selective Nitrous Oxide Oxidation for C-H Oxidation and Aromatization of 9,10-Dihydroanthracene Derivatives

YAMADA TOHRU

Chem. Lett. 2002   582 2002

Research paper (scientific journal), Joint Work, Accepted

The Enantioselective 1,3-Dipolar Cycloaddition of Nitrones Catalyzed by Optically Active Cationic Cobalt(III) Complexes

YAMADA TOHRU

Org. Lett. 4   2457-2460 2002

Research paper (scientific journal), Single Work, Accepted

Cobalt Carbene Complex with Single Bond Character: Intermediate for the Cobalt Complex Catalyzed Cyclopropanation

YAMADA TOHRU

J. Am. Chem. Soc., 124   15152-15153 2002

Research paper (scientific journal), Joint Work, Accepted

Efficient Preparation of C2-Symmetrical Chiral Ferrocenyldiols by Catalytic Enantioselective Reduction of Diacylferrocenes

YAMADA TOHRU

Org. Lett. 4   3313-3316 2002

Research paper (scientific journal), Joint Work, Accepted

β-ラクタム合成のルネサンス

YAMADA TOHRU

化学 57 ( 10 ) 60-61 2002

Research paper (scientific journal), Joint Work

Highly Enantioselective Cyclopropanation of Styrenes and Diazoacetates Catalyzed by 3-Oxobutylideneaminatocobalt(II) Complexes, Part 2. Semiempirical Analysis of Diastereo and Enantioselectivities

池野　健人・岩倉　いずみ・山田　徹

Bull. Chem. Soc. Jpn.(2001) Vol.74   2151-2160 2001.11

Joint Work

Highly Enantioselective Cyclopropanation of Styrenes and Diazoacetates Catalyzed by 3-Oxobutylideneaminatocobalt(II) Complexes, Part 1. Designs of Cobalt Complex Catalysts and the Effects of Donating Ligands

池野　健人・佐藤　光央・関野　啓之・西塚　麻惠・山田　徹

Bull. Chem. Soc. Jpn. (2001) Vol.74   2139-2150 2001.11

Joint Work

Highly Chemo-, Diastereo-, and Enantioselective Reduction of 2-Substituted-1,3-diketones for Alternative Preparation of Aldol-type Compounds

大塚　雄紀・小安　喜一郎・宮崎　大地・池野　健人・山田　徹

Org. Lett.(2001) Vol.3   3421-3424 2001.10

Joint Work

Nitrous Oxide Oxidation of Secondary and Benzylic Alcohols Using Ruthenium Complex Catalyst

橋本　健太郎・北市　泰範・田中　寛隆・池野　健人・山田　徹

Chem. Lett. 2001    922-923 2001.09

Joint Work

Enantioselective Borohydride Reduction of Ketones, Imines and Unsaturated Carboxamides Catalyzed by Optically Active Cobalt(II) Complex

Alambic (2001).  ( 62 ) 1 2001.08

Single Work

Reductive Desymmetrization of 2-Alkyl-1,3-diketones Catalyzed by Optically Active β-Ketoiminato Cobalt Complexes

大塚　雄紀・小安　喜一郎・池野　健人・山田　徹

Org. Lett. (2001) Vol.3   2543-2546 2001.08

Joint Work

Highly Diastereo- and Enantioselective Reduction of 1,3-Dicarbonyl Compounds Catalyzed by Optically Active β-Ketoiminato Cobalt Complexes

大塚　雄紀・小安　喜一郎・久保田　健・池野　健人・山田　徹

The 11th IUPAC Symposium on Organo-Metallic Chemistry directed toward Organic Symthesis  2001.07

Joint Work, Accepted

Highly Active 3-Oxobutylidene-aminatocobalt Complex Catalysts for Enantioselective Hetero Diels-Alder Reaction

毛塚　智子・美多　剛・大槻　奈津紀・池野　健人・山田　徹

Bull. Chem. Soc. Jpn. (2001) Vol.74   1333-1342 2001.07

Joint Work

Enantioselective Cyclopropanation Catalyzed by Optically Active β-Ketoiminato Cobalt(II) Complexes

山田　徹・池野　健人

The 17th International Symposium on Synthesis in Organic Chemistry  2001.07

Joint Work, Accepted

Optically Active β-Ketoiminato Cationic Cobalt(III) Complexes: Efficient Catalysts for Enantioselective Carbonyl-Ene Reaction of Glyoxal Derivatives

毛塚　智子・池野　健人・山田　徹

Org. Lett. (2001) Vol.3   1937-1940 2001.06

Joint Work

Highly Enantioselective Cyclopropanation Catalyzed by Optically Active b-Ketoiminato Cobalt(II) Complexes

M. Sato, A. Nishizuka, I. Iwakura, T. Ikeno, and T. Yamada

Catalysts and Fine Chemicals 2001  2001.03

Joint Work, Accepted

Highly Enantioselective Cyclopropanation in Alcoholic and Aqueous Solvents Catalyzed by Optically Active b-Ketoiminato Cobalt(II) Complex

T. Ikeno, A. Nishizuka, M. Sato, and T. Yamada

Synlett, 2001    406-408. 2001.03

Joint Work

(±)D-Aquabromo{3,3'-[(1R,2R)-1,2-bis(2,4,6-trimethylphenyl)ethane-1,2-diylbis (-nitrilomethylidene)]bis-(pentane-2,4-dionato)-N,N',O,O'}cobalt(III) tetrahydrofuran solvate

S. Ohba, T. Nagata and T. Yamada

Acta Crystallographica Section E, 2001    m124-m126. 2001.03

Joint Work

Nitrous Oxide Oxidation of Olefins Catalyzed by Ruthenium Porphyrin Complexes

T. Yamada, K. Hashimoto, Y. Kitaichi, K. Suzuki, and T. Ikeno

Chem. Lett., 2001    268-269. 2001.02

Joint Work

触媒的不斉酸化反応ー地球上で最も基本的な反応の精緻な制御ー

化学と工業(2002). 第55巻 ( 第1号 ) 7-11 2001.01

Research paper (scientific journal), Single Work

The Highly Enantioselective Borohydride Reductions of 2-Phenacylpyridine Catalyzed by Optically Active b-Ketoiminato Cobalt(II) Complexes

Y. Ohtsuka, T. Ikeno, and T. Yamada

Tetrahedron: Asymmetry, (2000)  ( 11 ) 3671-3674 2000.10

Joint Work

Ketoiminato Cobalt Complexes : A New Class of Catalysts for Asymmetric Synthesis

The 4th International Symposium: Transition Metals in Organic Synhesis  2000.09

Single Work, Accepted

Ketoiminato Cobalt Complex Catalyst for Enantioselective Hetero Diels-Alder Reaction

T. Yamada, S. Kezuka, T. Mita, and T. Ikeno

The 8th International Kyoto Conference on New Aspects of Organic Chemistry  2000.07

Joint Work, Accepted

Optically Active Cationic Cobalt(III) Complexes: Highly Efficient Catalysts for Enantioselective Hetero Diels-Alder Reaction

S. Kezuka, T. Mita, N. Ohtsuki, T. Ikeno, and T. Yamada

Chem. Lett., 2000    824-825. 2000.07

Joint Work

Convenient Preparation of Optically Pure 1,3-Diaryl-1,3-propanediols

Y. Ohtsuka, T. Kubota, T. Ikeno, T. Nagata, and T. Yamada

Synlett, 2000,    535-537 2000.04

Joint Work

Highly Enantioselective　Cyclopropanation of Styrenes with　Diazoacetates Catalyzed by　Optically Active b-Ketoiminato　Cobalt(II) Complexes,

T. Yamada, S. Kezuka, T. Mita, and T. Ikeno

Heterocycles, (2000)  ( 52　 ) 1041-1045 2000.03

Joint Work

Ketoiminato Cobalt Complexes: A　New Class of Catalysts for　Asymmetric Synthesis

The Nagoya COE-RCMS　Conference on Material Science and　Organic Chemistry in　the 21 st Century  2000.01

Single Work

N2O Oxidation of Phosphines　Catalyzed by Low-Valent Nickel　Complexes,

T. Yamada, K. Suzuki, K. Hashimoto, and T. Ikeno

Chem. Lett., 1999    1043-1044 1999.10

Joint Work

Optically Active AldiminatoCobalt(I Catalysts for Enantioselective I) Complexes as Efficient Cyclopropanation of Styrenes with Diazoacetates,

T. Yamada, T. Nagata, T. Ikeno, Y.Ohtsuka, A. Sagara, and T. Mukaiyama,

Chem. Lett., 1999,  1999.08

Joint Work

Selective 1,4-Reduction of a,b　Unsaturated Carbonyl Compounds by　Combined Use of Bis(1,3 diketonato)cobalt(II) Complex and　Diisobutylaluminium　Hydride

T. Yamada, T. Ikeno, H. Sekino, and M. Sato

Synlett, 1999    719-720 1999.01

Joint Work

Enantioselective Borohydride　 1,4-Reduction of a,b Unsaturated　Carboxamides Using Optically　Active Cobalt(II) Complex Catalysts

Chemistry Letteers,1998    1129-1130 1998.11

Joint Work

New and Efficient Catalysts　 for Enantioselective　Borohydride Reduction of　Ketones and Imines

Catalysis Surveysfrom Japan(1998)  ( 2 ) 47-57 1998.04

Joint Work

New and Efficient Catalysts for Enantioselective Borohydride Reduction of Ketones and Imines

永田卓司，杉　清明，萬　清隆，山田　徹，向山光昭

Catalysis Surveys from Japan Vol.2 1998

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体触媒によるケトン類イミン類の不斉ボロヒドロド還元反応について詳細に解説した。（１１頁）

Enantioselective Borohydride 1,4-Reduction of a,b-Unsaturated Carboxamides Using Optically Active Cobalt(II) Complex Catalysts

山田　徹，大塚雄紀，池野健人

Chem. Lett., 1998  1998

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体を触媒とすると不飽和カルボン酸アミドの１，４-不斉ボロヒドリド還元が顕著に加速され対応する光学活性カルボン酸アミドが得られることを報告した。（２頁）

Selective 1,4-Reduction of a,b-Unsaturated Carbonyl Compounds by Combined Use of Bis(1,3-diketonato)cobalt(II) Complex and Diisobutylaluminium Hydride

池野健人，木村友美，大塚雄紀，山田　徹

Synlett, 1998  1998

Joint Work

　View Summary

アセチルアセトナトコバルト錯体とジイソブチルアルミニウムから調製されるコバルトヒドリドは種々の不飽和カルボニル化合物の１，４-還元反応に効果的な試薬であることを明らかにした。（３頁）

Living Ring-opening Polymerization of Lactones Using Cationic Zirconocene Complex Catalyst

早川道也，三谷　誠，山田　徹，向山光昭

Macromolecular Chemistry and Physics  ( 198 )  1997

Joint Work

　View Summary

カチオン性ジルコノセン錯体触媒によるラクトンや環状炭酸エステルの開環重合ないし開環共重合について，これらがリビング重合であることを明らかにした。（１３頁）

Enantioselective Borohydride Reduction of N-Diphenylphosphinyl Imines Using Optically Active Cobalt(II) Complex Catalysts

杉　清明，永田卓司，山田　徹，向山光昭

Chem. Lett., 1997  1997

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体を触媒とする不斉ボロヒドリド還元が，ホスフィニルイミンの不斉還元にも適用可能であることを報告。（２頁）

簡便な1,2-ジアミンの合成法の開発

今川清水，秦英一郎，山田　徹，向山　光昭

日本化学会誌, 1997  1997

Research paper (scientific journal), Joint Work

　View Summary

一酸化窒素によるオレフィンのニトロ化反応と引き続くジオール化反応について詳細に報告。（６頁）

一酸化窒素によるオレフィン類の窒素化反応

秦英一郎・加藤穂慈・山田　徹・向山光昭

有機合成化学協会誌 4 ( 9 ) 728 - 739 1996.09

Research paper (scientific journal), Joint Work, Accepted

　View Summary

酸化窒素によるオレフィン類の窒素官能基化反応について解説した。（１２頁）

Novel Zirconium-iron Multinuclear Complex Catalysts for Olefin Polymerization

三谷　誠，大内邦弘，早川道也，山田　徹，向山光昭

Bull. Chem. Soc. Jpn  ( 69 )  1996

Joint Work

　View Summary

新規なジルコノセン複核錯体によるオレフィンの重合について詳細に報告した。（１０頁）

Convenient Method for One-pot Preparation of 1,2-Diamines from Nitroolefins

今川清水，秦英一郎，山田　徹，向山光昭

Chem. Lett., 1996  1996

Joint Work

　View Summary

ニトロオレフィンを簡便に１，２-ジアミンに変換する反応について報告。（２頁）

Enantioselective Borohydride Reduction of Ketones Catalyzed by Optically Active Cobalt(II) Complexes: Achievement of High Enantioselection by Modified Borohydrides with Fufuryl Alcohol Derivatives

杉　清明，永田卓司，山田　徹，向山光昭

Chem. Lett., 1996  1996

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体を触媒とする不斉ボロヒドリド還元において水素化ホウ素ナトリウムをフルフリルアルコールで修飾活性化すると光学収率が向上することを報告。（２頁）

Effects of Ligands and Additive Alcohols on Enantioselection in Highly Efficient Asymmetric Borohydride Reduction of Ketones Catalyzed by Optically Active Aldiminato Cobalt(II) Complexes

永田卓司，杉　清明，山田　徹，向山光昭

Synlett, 1996  1996

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体を触媒とする不斉ボロヒドリド還元においてコバルト錯体の配位子と不斉収率の関係をＸ線結晶構造解析の結果も踏まえて検討した。（３頁）

Practical Enantioselective Borohydride Reduction of Aromatic Ketones Catalyzed by Optically Active Cobalt(II) Complexes Using Pre-modified Borohydride

杉　清明，永田卓司，山田　徹，向山光昭

Chem. Lett., 1996  1996

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体を触媒とする不斉ボロヒドリド還元において，水素化ホウ素ナトリウムをフルフリルアルコールであらかじめ処理することにより反応効率が格段に向上することを報告。（２頁）

Ethylene Oligomerization Catalyzed by Dichlorobis(b-diketonato)zirconium / Organoaluminum Compounds

大内邦弘，三谷　誠，早川道也，山田　徹，向山光昭

Macromolecular Chemistry and Physics  ( 197 )  1996

Joint Work

　View Summary

βジケトナトジルコニウム錯体によるオレフィンのオリゴメリ化反応について報告。（６頁）

Novel Zirconacyclopentadiene Complex; 8,8-Bis(cyclopentadienyl)-7,9-bis(trimethylstannyl)- 8-zirconabicyclo[4.3.0]nona-1(9),6(7)-diene: Synthesis, X-Ray Analysis, and Catalytic Activity for Ethylene Polymerization

大内邦弘，三谷　誠，早川道也，山田　徹，向山光昭

J. Organomet. Chem  ( 516 )  1996

Joint Work

　View Summary

ジルコナシクロペンタジエン錯体のエチレン重合活性じついてＸ線結晶構造解析の結果に基づいて検討した。（４頁）

Ligand Effects on Olefin Polymerizations with Mutinuclear Zirconocene Catalysts Having Dimethylsilylferrocene as a Cyclopentadienyl Substituent

三谷　誠，大内邦弘，早川道也，山田　徹，向山光昭

Macromolecular Chemistry and Physics  ( 197 )  1996

Joint Work

　View Summary

二核ジルコノセン錯体の則鎖の置換基が重合活性に及ぼす影響について系統的に検討した。（８頁）

Living Ring-oening Polymerization of Cyclic Carbonate Using Cationic Zirconocene Complex Catalyst

早川道也，三谷　誠，山田　徹，向山光昭

Makromol. Rapid Commun  ( 17 )  1996

Joint Work

　View Summary

カチオン性ジルコノセン錯体が環状炭酸エステルの開環重合の触媒となることを報告した。（６頁）

Recent Advances in Aerobic Oxygenation

向山光昭，山田　徹

Bull. Chem. Soc. Jpn Vol.68 1995.01

Joint Work

　View Summary

酸化還元的水和反応から酸素不斉エポキシ化反応に至るまで酸素酸化反応の研究展開を大局的な立場から解説した。（１９頁）

分子状酸素を用いる不斉エポキシ化反応 光学活性マンガン(III)錯体触媒の設計と合成

山田　徹・永田卓司・向山光昭

日本化学会誌    755 - 762 1995

Research paper (scientific journal), Joint Work, Accepted

　View Summary

酸素不斉エポキシ化反応について主に錯体触媒の配位子の設計の観点から解説した。（８頁）

Convenient and Simple Preparation of Nitroolefins, Nitration of Olefins with Nitric Oxide

向山光昭，秦英一郎，山田　徹

Chem. Lett., 1995  1995

Joint Work

　View Summary

一酸化窒素によりオレフィンが対応するニトロオレフィンに変換されることを報告。（２頁）

A Convenient Method for the Preparation of Nitro Olefins by Nitration of Olefins with Nitrogen Monoxide

秦英一郎，山田　徹，向山光昭

Bul. Chem. Soc. Jpn  ( 68 )  1995

Joint Work

　View Summary

一酸化窒素によるオレフィンのニトロ化反応の詳細について報告。（８頁）

Enantioselective Reduction of Ketones with Sodium Borohydride Catalyzed by Optically Active b-Oxo Aldiminato Cobalt(II) Complexes

永田卓司，萬　清隆，山田　徹，向山光昭

Angew. Chem. Int. Ed. Engl  ( 34 )  1995

Joint Work

　View Summary

光学活性ケトイミナト型コバルト錯体を触媒として用いると水素化ホウ素ナトリウムによる不斉還元反応が実現できることを報告した。（３頁）

Mono-aryloxy or Mono-alkoxy Zirconium Complexes / Methylaluminoxane Catalyst System in Ethylene Polymerization

三谷　誠，大内邦弘，早川道也，山田　徹，向山光昭

Polymer Bulletin  ( 34 )  1995

Joint Work

　View Summary

アルコキシジルコニウム錯体のエチレン重合触媒活性について検討した。（４頁）

Preparation of Narrow Polydispersity Polycaprolactone Catalyzed by Cation Zirconocene Complexes

向山光昭，早川道也，大内邦弘，三谷　誠，山田　徹

Chem. Lett., 1995  1995

Joint Work

　View Summary

カチオン性ジルコノセン錯体がカプロラクトンの開環重合の触媒として有効であることを報告。（２頁）

Stereoselective Cyclopolymerization of 1,5-Hexadiene Using Novel Bis(ferrocenyl)zirconocene Catalyst

三谷　誠，大内邦弘，早川道也，山田　徹，向山光昭

Chem. Lett., 1995  1995

Joint Work

　View Summary

ビスフェロセニルジルコノセン錯体は立体選択的な１，５-ヘキサジエンの環化重合触媒となることを報告。

Olefin Polymerization Catalyzed by Homo- and Heterobimetallic Zirconocene Complexes / Methylalminoxane System

三谷　誠，大内邦弘，早川道也，山田　徹，向山光昭

Polymer Bulletin  ( 35 )  1995

Joint Work

　View Summary

二核ジルコノセン錯体触媒によるオレフィン重合について詳細に報告。（６頁）

Enantioselective Aerobic Oxidation of Sulfides Catalyzed by Optically Active b-Oxo Aldiminato Manganese(III) Complexes

永田卓司，今川清水，山田　徹，向山光昭

Bull. Chem. Soc. Jpn  ( 68 )  1995

Joint Work

　View Summary

光学活性ケトイミナト型マンガン錯体触媒によるスルフィドの不斉酸化反応について詳細に報告。（６頁）

Optically Active N,N'-Bis(3-oxobutylidene)diaminatomanganese(III) Complexes as Novel and Efficient for Aerobic Enantioselective Epoxidation of Simple Olefins

永田卓司，今川清水，山田　徹，向山光昭

Bull. Chem. Soc. Jpn  ( 68 )  1995

Joint Work

　View Summary

光学活性ケトイミナト型マンガン錯体触媒による酸素不斉エポキシ化反応について詳細に報告。（１１頁）

Asymmetric Oxidation of Sulfides with Molecular Oxygen Catalyzed by b-Oxo Aldiminato Manganese(III) Complexes

今川清水，永田卓司，山田　徹，向山光昭

Chem. Lett., 1995  1995

Joint Work

　View Summary

光学活性ケトイミナト型マンガン錯体触媒を用いると分子状酸素によってスルフィドの不斉酸化反応が行なわれることを報告。（４頁）

酸素酸化反応の新しい可能性

ペトロテック 第17巻 1994.02

Single Work

　View Summary

ニッケル錯体触媒などの遷移金属錯体とアルデヒドを組み合わせ用いる常温常圧酸素エポキシ化反応について平易に解説。（６頁）

Direct and Stereoselective Conversion of Styrene Oxide into Optically Active 1,3-Dioxolane

永田卓司，高井敏浩，山田　徹，今川清水，向山光昭

Bull. Chem. Soc. Jpn  ( 67 )  1994

Joint Work

　View Summary

種々の光学活性スチレンオキシドがルイス酸の存在下，ケトンとの反応で光学活性を失うことなく対応する保護されたジオールに変換されることを報告した。（３頁）

A Novel Method for the Preparation of Acid-sensitive Epoxides from Olefins with Combined Use of Molecular Oxygen and Acetal of Aldehyde Catalyzed by Cobalt(II) Complex

萬　清隆，高井敏浩，山田　徹，向山光昭

Bull. Chem. Soc. Jpn  ( 67 )  1994

Joint Work

　View Summary

コバルト錯体触媒とプロピオン酸ジエチルアセタールの共存下で行う，酸性に敏感な化合物の酸素エポキシ化反応について詳細に報告。（８頁）

Direct Oxygenation of Benzene and Its Analogues into Phenols Catalyzed by Oxovanadium(IV) Complex with Combined Use of Molecular Oxygen and Aldehyde

秦英一郎，高井敏浩，山田　徹，向山光昭

Chem. Lett., 1994  1994

Joint Work

　View Summary

オキソバナジウム錯体触媒の存在下，分子状酸素とアルデヒドの組み合わせにより芳香族化合物が水酸基化されフェノール類が得られることを報告。（４頁）

N-Alkyl Imidazoles as Efficient Axial Ligands in the Aerobic Asymmetric Epoxidation of Unfunctionalized Olefins Catalyzed by Optically Active Manganese(III)-salen-type Complex

今川清水，永田卓司，山田　徹，向山光昭

Chem. Lett., 1994  1994

Joint Work

　View Summary

光学活性マンガン錯体触媒による酸素エポキシ化反応において，Ｎ-アルキルイミダゾール類が効果的な軸配位子となることを報告。（４頁）

Aerobic Enantioselective Epoxidation of Unfunctionalized Olefins Catalyzed by Optically Active Salen-Manganese(III) Complexes

山田　徹，今川清水，永田卓司，向山光昭

Bull. Chem. Soc. Jpn  ( 67 )  1994

Joint Work

　View Summary

光学活性サレン型マンガン錯体触媒による酸素不斉エポキシ化反応の詳細について報告。（９頁）

Optically Active b-Ketoiminato Manganese(III) Complexes as Efficient Catalysts in Enantioselective Aerobic Epoxidation of Unfunctionalized Olefins

永田卓司，今川清水，山田　徹，向山光昭

Inorg. Chim. Acta  ( 220 )  1994

Joint Work

　View Summary

酸素不斉エポキシ化反応の触媒となる光学活性ケトイミナト型マンガン錯体の立体構造をＸ線結晶構造解析により明らかにした。（５頁）

Enantioselective Aerobic Epoxidation of Acyclic Olefins Catalyzed by the Optically Active b-Ketoiminato Manganese(III) Complex

永田卓司，今川清水，山田　徹，向山光昭

Chem. Lett., 1994  1994

Joint Work

　View Summary

光学活性ケトイミナト型マンガン錯体を触媒として用いると鎖状オレフィンの酸素不斉エポキシ化が実現されることを報告。（４頁）

A Convenient Method for the Preparation of Acetal Carboxylic Acids by Nickel(II) Complex Catalyzed Oxygenation of a-Alkoxy Cyclic Ketones with Molecular Oxygen

秦英一郎，高井敏浩，山田　徹，向山光昭

Chem. Lett., 1994  1994

Joint Work

　View Summary

ニッケル錯体触媒によるとαアルコキシ環状ケトンが酸素分子によって酸化的に開環することを報告。（４頁）

酸素酸化反応の新しい可能性

山田　徹・高井敏浩・向山光昭

有機合成化学協会誌 第51巻 1993.11

Research paper (scientific journal), Joint Work

　View Summary

アルコールやアルデヒドなどの還元剤として作用する化合物を共存させることにより酸素分子を酸化剤とする酸化反応が実現されるようになることを解説した。（１０頁）

Epoxidation of Olefinic Compounds with Combined Use of Molecular Oxygen and Propionaldehyde Diethyl Acetal Catalyzed by Cobalt(II) Complex. Efficient Method for the Preparation of Acid-sensitive Epoxides

萬　清隆，高井敏浩，山田　徹，向山光昭

Chem. Lett., 1993  1993

Joint Work

　View Summary

コバルト錯体触媒とプロピオン酸ジエチルアセタールの共存下での酸素エポキシ化反応は酸性条件に敏感な化合物のエポキシ化を中性条件で行うことができることを報告。（４頁）

Asymmetric Aerobic Epoxidation of Unfunctionalized Olefins Catalyzed by Optically Active a-Alkoxycarbonyl-b-ketoiminato Manganese(III) Complexes

向山光昭，山田　徹，永田卓司，今川清水

Chem. Lett., 1993  1993

Joint Work

　View Summary

光学活性ケトイミナト型マンガン錯体触媒の存在下，分子状酸素とアルデヒドにより特別な官能基を持たないオレフィンの酸素不斉エポキシ化反応が実現できることを報告。（４頁）

Aerobic Epoxidation of Olefins Catalyzed by Cobalt(II) Complex Using Propionaldehyde Diethyl Acetal as a Reductant

向山光昭，萬　清隆，高井敏浩，山田　徹

Chem. Lett., 1993  1993

Joint Work

　View Summary

コバルト錯体触媒とプロピオン酸ジエチルアセタールの共存下，酸素エポキシ化反応が進行することを報告。（４頁）

ニッケル(II)錯体触媒を用いる酸素エポキシ化反応

触媒 第34巻 1992.07

Research paper (scientific journal), Single Work

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ニッケル錯体触媒などの遷移金属錯体とアルデヒドを組み合わせ用いる常温常圧酸素エポキシ化反応について平易に解説。（２頁）

分子状酸素によるエポキシドの常温常圧合成

化学と工業 第45巻 1992.05

Research paper (scientific journal), Single Work

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ニッケル錯体触媒などの遷移金属錯体とアルデヒドを組み合わせ用いる常温常圧酸素エポキシ化反応について解説。（３頁）

b-Selective Epoxidation of Cholesterol Derivatives with Molecular Oxygen and Aldehyde Catalyzed by Manganese(II) Complex

山田　徹，今川清水，向山光昭

Chem. Lett., 1992  1992

Joint Work

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マンガン錯体触媒の存在下，分子状酸素とアルデヒドによりステロイド骨格のエポキシ化を行うと通常と異なりβ選択的にエポキシドが得られることを報告。（４頁）

A Novel Method for the Preparation of Optically Active Dipeptide. Chemo- and Stereoselective Reduction of 2-Hydroxyimino Amides with Samarium Diiodide

向山光昭，萬　清隆，加藤穂慈，山田　徹

Chem. Lett., 1992  1992

Joint Work

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２-ヒドロキシイミノカルボン酸アミドがヨウ化サマリウムで立体選択的に還元され対応するペプチド誘導体を与えることを報告した。（４頁）

Enantioselective Epoxidation of Unfunctionalized Olefins with Molecular Oxygen and Aldehyde Catalyzed by Optically Active Manganese(III) Complexes

山田　徹，今川清水，永田卓司，向山光昭

Chem. Lett., 1992  1992

Joint Work

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光学活性マンガン錯体触媒の存在下，分子状酸素とアルデヒドによって特別な官能基を持たないオレフィンの不斉酸素エポキシ化が実現できることを報告。（４頁）

Aerobic Epoxidation of Olefinic Compounds Catalyzed by Tris(1,3-diketonato)iron(III)

高井敏浩，秦英一郎，山田　徹，向山光昭

Bull. Chem. Soc. Jpn  ( 64 )  1992

Joint Work

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触媒量の鉄錯体の存在下，分子状酸素とアルデヒドを組み合わせ用いるとスチレン類のエポキシ化が選択性良く実現されることを報告。（６頁）

A Novel Method for Preparation of Glycerol Monoesters from Glycidyl Esters with Molecular Oxygen Catalyzed by Ni(II) Complex

向山光昭，今川清水，山田　徹，高井敏浩

Chem. Lett., 1992  1992

Joint Work

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グリシジルエーテルをニッケル錯体触媒により酸素酸化すれば簡便にグリセロールモノエステルに変換できることを報告。（４頁）

Oxidation of Aldehydes into Carboxylic Acids with Molecular Oxygen Using Nickel(II) Complex Catalyst

山田　徹，オリバー・ローデ，高井敏浩，向山光昭

Chem. Lett., 1991  1991

Joint Work

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ニッケル錯体触媒の存在下，アルデヒドが酸素酸化によってカルボン酸に容易に変換されることを報告。（４頁）

Highly Efficient Method for Epoxidation of Olefins with Molecular Oxygen and Aldehydes Catalyzed by Nickel(II) Complexes

山田　徹，高井敏浩，オリバー・ローデ，向山光昭

Chem. Lett., 1991  1991

Joint Work

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触媒量のニッケル錯体の存在下，分子状酸素とアルデヒドを組み合わせ用いると種々のオレフィンの酸素エポキシ化反応が常温常圧で実現されることを報告。（４頁）

Direct Epoxidation of Olefins Catalyzed by Nickel(II) Complexes with Molecular Oxygen and Aldehydes

山田　徹，高井敏浩，オリバー・ローデ，向山光昭

Bull. Chem. Soc. Jpn  ( 64 )  1991

Joint Work

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ニッケル錯体触媒による常温常圧酸素エポキシ化反応について詳細に報告。（９頁）

Oxygenation of Silyl Enol Ethers and Silyl Ketene Acetals with Molecular Oxygen and Aldehyde Catalyzed by Nickel(II) Complex. A Convenient Method for the Preparation of a-Hydroxy Carbonyl Compounds

高井敏浩，山田　徹，オリバー・ローデ，向山光昭

Chem. Lett., 1991  1991

Joint Work

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シリルエノールエーテルをニッケル錯体触媒によって酸素酸化するとαヒドロキシカルボニル化合物が得られることを報告。（４頁）

Aerobic Oxygenation of Olefinic Compounds into the Corresponding a-Hydroxy Ketones Using the Catalysts System of OsO4 and Ni(II) Complex

高井敏浩，山田　徹，向山光昭

Chem. Lett., 1991  1991

Joint Work

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触媒量の四酸化オスミウムとニッケル錯体の存在下，オレフィンの酸素酸化を行うとαヒドロキシケトンを合成することができる。（４頁）

Oxovanadium(IV) Complex Catalyzed Oxygenation of a,b-Unsaturated Carboxamide into 2,3-Epoxycarboxamide with Molecular Oxygen and an Aldehyde

猪木　哲，高井敏浩，山田　徹，向山光昭

Chem. Lett., 1991  1991

Joint Work

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オキソバナジウム錯体の存在下，アルデヒドと分子状酸素によって不飽和カルボン酸アミドがエポキシ化されることを報告。（４頁）

The Baeyer-Villiger Oxidation of Ketones Catalyzed by Nickel(II) Complexes with Combined Use of Molecular Oxygen and an Aldehyde

山田　徹，高橋克也，加藤穂慈，高井敏浩，猪木　哲，向山光昭

Chem. Lett., 1991  1991

Joint Work

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ニッケル錯体触媒の存在下，分子状酸素とアルデヒドにより酸素バイヤービリガー反応が実現されることを報告。（４頁）

Nickel(II) Complex Catalyzed Epoxidation of Olefins with Molecular Oxygen and Primary Alcohol

向山光昭，高井敏浩，山田　徹，オリバー・ローデ

Chem. Lett., 1990  1990

Joint Work

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触媒量のニッケル錯体の存在下，３置換オレフィンの酸素エポキシ化が実現されることを報告。（４頁）

4-O-Benzyl-2,3-O-isopropylidene-L-threose: A Useful Building Block for Stereoselective Synthesis of Monosaccharides

向山光昭，鈴木啓介，山田　徹，田房不二男

Tetrahedron  ( 46 )  1990

Joint Work

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単糖類の立体選択的合成素子として有用なＬ-トレオース誘導体の反応について報告。（１２頁）

Catalytic Oxidation-Reduction Hydration of Olefins with Molecular Oxygen in the Presence of Bis(1,3-diketonato)cobalt(II) Complexes

加藤穂慈，山田　徹，高井敏浩，猪木　哲，諫山　茂

Bull. Chem. Soc. Jpn  ( 63 )  1990

Joint Work

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触媒量のコバルト錯体の存在下，酸素分子による酸化還元的水和反応について詳細を報告。（７頁）

Epoxidation of Olefins with Molecular Oxygen and Alcohol Catalyzed by Bis(2-alkyl-1,3-diketonato)oxovanadium(IV)

高井敏浩，山田　徹，向山光昭

Chem. Lett., 1990  1990

Joint Work

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触媒量のオキソバナジウム錯体の存在下，ノルボルネン類の酸素エポキシ化反応が実現されることを報告。（４頁）

Novel Method for Oxidation of Secondary Alcohols into Ketones with Molecular Oxygen by Using Cobalt(II) Complex Catalyst

山田　徹，向山光昭

Chem. Lett., 1989  1989

Joint Work

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コバルト錯体を触媒として用いると２級アルコールの酸素酸化反応が実現されることを報告。（４頁）

Asymmetric Diels-Alder Reaction Catalyzed by a Chiral Titanium Reagent

奈良坂紘一，岩澤伸治，井上正之，山田　徹，中島雅子，杉森　純

J. Am. Chem. Soc  ( 111 )  1989

Joint Work

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光学活性チタン錯体触媒による不斉ディールス-アルダー反応の詳細について報告。（４頁）

Oxidation-Reduction Hydration of Olefins with Molecular Oxygen and 2-Propanol Catalyzed by Bis(acetylacetonato)cobalt(II)

向山光昭，諫山　茂，猪木　哲，加藤穂慈，山田　徹，高井敏浩

Chem. Lett., 1989  1989

Joint Work

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コバルト錯体触媒の存在下，２-プロパノールと酸素分子によってオレフィンが酸化還元的に水和されることを報告。（４頁）

Bis(trifluoroacetylacetonato) cobalt(II) Catalyzed Oxidation-Reduction Hydration of Olefins Selective Formation of Alcohols from Olefins

猪木　哲，加藤穂慈，高井敏浩，諫山　茂，山田　徹，向山光昭

Chem. Lett., 1989  1989

Joint Work

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酸化還元的水和反応で用いるコバルト錯体の配位子に電子求引性置換基を導入すると水和生成物の選択性が向上することを報告。（４頁）

Asymmetric Hydrocyanation of Aldehydes Using Chiral Titanium Reagents

南川博之，早川聡，山田　徹，岩澤伸治，奈良坂紘一

Bull. Chem. Soc. Jpn  ( 61 )  1988

Joint Work

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光学活性チタン錯体を触媒とする不斉ヒドロシアノ化反応の詳細について報告。（５頁）

Asymmetric Diels-Alder Reaction by the Use of a Chiral Titanium Catalyst with Molecular Sieves 4A. Remarkable Solvent Effect on the Enantioselectivity

奈良坂紘一，井上正之，山田　徹，杉森　純，岩澤伸治

Chem. Lett., 1987  1987

Joint Work

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光学活性チタン錯体触媒による不斉ディールス-アルダー反応におけるモレキュラーシーブスの添加効果，不斉収率に対する顕著な溶媒効果について報告。（４頁）

The Asymmetric Addition oh the Sn(II) Enolates of Thioesters to a-Iminoesters. A Convenient Synthesis of Optically Active cis-Substituted b-Lactams

山田　徹，鈴木裕史，向山光昭

Chem. Lett., 1987  1987

Joint Work

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チオエステルのスズエノラートのイミノエステルへの付加反応により光学活性シスβ-ラクタムが簡便に合成できる方法を開発。（４頁）

The Asymmetric Hydrocyanation of Aldehydes with Cyanotrimethylsilane Promoted by a Chiral Titanium Reagent

奈良坂紘一，山田　徹，南川博之

Chem. Lett., 1987  1987

Joint Work

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光学活性チタン錯体を触媒とするとアルデヒドに対して不斉ヒドロシアノ化反応が実現されることを報告。（４頁）

The Asymmetric Diels-Alder Reaction by the Use of a Catalytic Amount of a Chiral Titanium Reagent

奈良坂紘一，井上正之，山田　徹

Chem. Lett., 1986  1986

Joint Work

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触媒量の光学活性チタン錯体を用いる不斉ディールス-アルダー反応を報告。（２頁）

Asymmetric Oxidation of Olefins with Osmium Tetraoxide Coordinated by Chiral Diamines Derived from L-Tartaric Acid

山田　徹，奈良坂紘一

Chem. Lett., 1986  1986

Joint Work

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光学活性ジアミンを配位子とするオスミウム錯体によるオレフィンの不斉ジオール化反応について報告。（４頁）

The Diastereoselective Addition of Tin(II) Enolates Derived from Carboxylic Thioesters to a-Iminoesters

向山光昭，鈴木裕史，山田　徹

Chem. Lett., 1986  1986

Joint Work

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カルボン酸チオエステルから発生させたスズエノラートのイミノエステルに対するジアステレオ選択的付加反応について報告。（４頁）

A Formal Total Synthesis of Polyoxin J using 4-O-Benzyl-2,3-O-isopropylidene-L-threose as a Comon Chiral Building Block

田房不二男，山田　徹，鈴木啓介，向山光昭

Chem. Lett., 1984  1984

Joint Work

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酒石酸から合成されるＬ-トレオース誘導体を合成素子として，ポリオキシンＪを選択的に形式全合成した。（４頁）

Stereoselective Synthesis of L-Sugars of Biological Importance Starting from 4-O-Benzyl-2,3-O-isopropylidene-L-threose as a Chiral Building Block

向山光昭，鈴木啓介，山田　徹

Chem. Lett., 1983  1983

Joint Work

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酒石酸から合成されるＬ-トレオース誘導体を合成素子として種々のＬ-糖の合成法を提案した。（４頁）

4-O-Benzyl-2,3-isopropylidene-L-threose --- A New and Useful Building Block for the Syntheses of L-Sugars ---

向山光昭，鈴木啓介，山田　徹

Chem. Lett., 1982  1982

Joint Work

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Ｌ-糖の合成のための合成素子を酒石酸を原料として開発した。（４頁）