Papers - Manabe, Tomohiro

マラソンの大会救護体制

真鍋知宏

臨床スポーツ医学 (文光堂)  42 ( 7 ) 743 - 747 2025.07

Research paper (scientific journal), Single Work, Lead author, Corresponding author

Strategies for Reducing Sudden Cardiac Death by Raising Public Awareness - A Statement From the Education and Implementation for Cardiac Emergency Committee of the Japanese Circulation Society -

Nishiyama C., Yoshimura S., Taniguchi T., Amano T., Ando H., Homma Y., Imamura T., Itoh T., Kiguchi T., Kiyohara K., Konno S., Makimoto H., Manabe T., Matsuzawa Y., Mitamura H., Niwamae N., Sakuma M., Sato K., Satoh Y., Tahara Y., Tsujita K., Tsukada Y.T., Uchida M., Ueda Y., Iwami T.

Circulation Journal 89 ( 3 ) 394 - 418 2025.03

ISSN  13469843

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Differences in athlete’s left ventricular morphology by sex and sports discipline categories in elite Japanese athletes

Ashikaga K., Manabe T., Tomori A., Endo N., Kamahara K.

Physician and Sportsmedicine  2025

ISSN  00913847

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Objectives: The cardiac morphology of elite athletes is related to sports disciplines and race; however, no studies have examined the effects of sports discipline on East Asian athletes. Therefore, this study aimed to assess left ventricular (LV) remodeling using transthoracic echocardiography in elite Japanese athletes and establish standard values for the indicators of the cardiac morphology of elite athletes in East Asia, considering the influence of body size. Methods: We retrospectively evaluated 1,363 elite Japanese athletes who underwent electrocardiography and transthoracic echocardiography between January 2011 and December 2021. The athletes were assigned to four sports discipline categories (skill, power, mixed, and endurance). We evaluated the differences in LV volume and mass between the groups for each sex. Results: The LV end-diastolic volume (LVEDV) and LV mass indexed to the body surface area (BSA) in the endurance group (LVEDV/BSA: 72.3 ± 11.4 mL/m2 in males and 68.7 ± 11.0 mL/m2 in females, LV mass/BSA: 121.1 ± 19.1 g/m2 in males and 106.5 ± 18.0 g/m2 in females) were significantly larger than those of any other groups. Both values were affected by sex, BSA, and endurance sport type, whereas only LV mass was affected by age. Conclusion: Cardiac remodeling is proportional to the sport type, with a significantly greater effect in athletes playing endurance sports. The remodeling is particularly evident in the left ventricle; however, the corresponding remodeling is also observed in other heart chambers. Cardiac remodeling in elite Japanese athletes is similar to that observed in elite athletes of other races, except for the changes in LV wall thickness.

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Sudden cardiac arrest during marathons among young, middle-aged, and senior runners

Manabe T., Kato J., Yamasawa F.

Resuscitation 204 2024.11

Lead author, Corresponding author,  ISSN  03009572

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Aim: There is limited evidence showing a relationship with age in the incidence of sudden cardiac arrest during exercise, which can be lethal at times. Methods: To examine the incidence by age group in sudden cardiac arrest, we prospectively observed cases of sudden cardiac arrest in full marathons certified by the Japan Association of Athletics Federations held between April 2011 and March 2019. Sudden cardiac arrest was defined as collapse during or 1 h after the race requiring chest compressions or the use of an automatic electrical defibrillation. Results: 4.1 million persons ran in 516 marathons. Of the participants, 78.6 % were men. By age group, 37.4 %, 34.7 %, 19.6 %, and 8.3 % belonged to the < 40 s, 40 s, 50 s, and ≥ 60 s groups, respectively. During the study period, 69 sudden cardiac arrests (1.7 per 100,000 participants, 95 % confidence interval [CI]: 1.3–2.1) were observed, of which 66 were men. The incidence per 100,000 runners of sudden cardiac arrest was 0.9 (95 % CI: 0.4, 1.4), 0.9 (95 % CI: 0.4, 1.4), 2.6 (95 % CI: 1.5, 3.8), and 5.5 (95 % CI: 2.9, 8.2) for those in their under 40 s, 40 s, 50 s, and over 60 s, respectively, with higher rates for older age groups. Compared to men, the cases of SCA among women were less common (only three cases), and the incidence did not differ by age group. Conclusions: Men, unlike women, had a higher incidence of sudden cardiac arrest during marathons according to age. Identification of this high-risk population could be important information in encouraging marathoners pre-participation self-screening.

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Prevalence of anemia and iron deficiency and its association with body mass index in elite Japanese high school long-distance runners

Shogo Tabata, Yuka Tsukahara, Hiroshi Kamada, Tomohiro Manabe, Fumihiro Yamasawa

The Physician and Sportsmedicine (Physician and Sportsmedicine)   2023.10

Research paper (scientific journal), Joint Work, Accepted,  ISSN  00913847

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Objectives: Anemia is a common condition in long-distance runners (LDRs). Recently, not only iron deficiency (ID) but also energy deficiency has been considered as a risk factor for anemia in athletes but no evidence has yet been established. The aim of this study was to investigate the prevalence of anemia and ID and the influence of body mass index (BMI) on anemia in high-school LDRs. Methods: The participants were 406 male and 235 female elite Japanese LDRs who competed in the All-Japan High-School Ekiden Championship 2019. They submitted their anthropometric data and results of a blood test within five days after the competition. The prevalence of anemia and ID and the influence of BMI on anemia were assessed retrospectively. Results: Mean hemoglobin concentrations (Hb) were 14.8 ± 0.9 g/dl in males and 13.2 ± 0.9 g/dl in females. The prevalence of anemia (Hb < 14 g/dl in males and < 12 g/dl in females) was significantly higher in males (16.3%) than females (6.4%), but males also showed higher prevalence of non-iron deficiency anemia (NIDA) than females (11.6% and 3.0%, respectively). No significant gender difference was found in the prevalence of iron deficiency anemia (IDA) (4.7% in males and 3.4% in females). ID (serum ferritin level < 25 ng/ml) was significantly more prevalent in females (37.4%) than males (18.5%). A binary logistic regression analysis revealed that low BMI was a contributor to anemia in females (odds ratios: 0.577 (95% CI: 0.369–0.901), p = 0.012). Conclusion: In Japanese high-school LDRs, one in six males was anemic, but most males did not have ID. Conversely, one-third of females were diagnosed with ID. Lower BMI was identified as a risk for anemia in females, suggesting that leanness may also lead to anemia in females.

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スポーツと循環器学

真鍋知宏

循環器ジャーナル (医学書院)  71 ( 1 ) 140 - 144 2023.01

Research paper (scientific journal), Single Work, Lead author, Corresponding author

陸上競技と感染症

真鍋　知宏

臨床スポーツ医学 (文光堂)  38 ( 8 ) 846 - 851 2021.08

Research paper (scientific journal), Single Work

医療体制の確保

真鍋　知宏

臨床スポーツ医学 (文光堂)  38 ( 2 ) 132 - 134 2021.02

Research paper (scientific journal), Single Work

痛み止めの効果とアンチ・ドーピング

真鍋　知宏

体育の科学 (杏林書院)  70 ( 10 ) 723 - 728 2020.10

Research paper (scientific journal), Single Work

Use of nutritional supplements by elite Japanese track and field athletes

Tabata S., Yamasawa F., Torii S., Manabe T., Kamada H., Namba A., Kato J., Kaneko H., Tahara K., Tsukahara Y., Sato K.

Journal of the International Society of Sports Nutrition (Journal of the International Society of Sports Nutrition)  17 ( 1 )  2020.07

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Background: While scientific evidence supports the efficacy of only limited nutritional supplements (NS) on sports performance, the use of NS is widespread in athletes. Given the serious issues of health damage or unintended Anti-Doping Rule Violations due to ingestion of contaminated NS in sports, accurately understanding NS practices by athletes is crucial. This study therefore elucidated the use of NS by elite Japanese track and field (TF) athletes. Methods: The subjects were 574 Japanese TF athletes, including 275 junior athletes (under 20 years) and 299 senior athletes, who participated in international competitions from 2013 to 2018. Data on NS use were collected through pre-participation medical forms obtained from all entrants before their participation in competitions. NS users were requested to report the product names and primary components of all NS they were taking. Results: The overall prevalence of NS use was 63.9%. The mean number of NS products used per athlete was 1.4. The prevalence was significantly higher in women (69.2%) than in men (59.6%) (p = 0.018) and significantly higher in senior athletes (68.9%) than in junior athletes (58.9%) (p = 0.012). The prevalence of NS use was higher in long-distance runners (75.8%) and lower in jumpers (52.3%) and throwers (49.2%) than other disciplines (p < 0.001). The most prevalent components were amino acids (49.3%), followed by vitamins (48.3%), minerals (22.8%), and protein (17.8%). Conclusions: Approximately two-thirds of elite Japanese TF athletes reported the use of NS, and NS practices varied by gender, age, and discipline.

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AEDと心肺蘇生

真鍋　知宏

臨床スポーツ医学 (文光堂)  37 ( 7 )  2020.07

Research paper (scientific journal), Single Work

スポーツ中の内因性重大事故の現状

真鍋　知宏

臨床スポーツ医学 (文光堂)  37 ( 6 ) 652 - 656 2020.06

Research paper (scientific journal), Single Work

スポーツと心電図変化：精査が必要な所見、人種差による特徴

真鍋　知宏

心臓 (日本心臓財団・日本循環器学会)  52 ( 4 ) 366 - 371 2020.04

Research paper (scientific journal), Single Work

Notes on medical management for pain from an anti-doping perspetive

真鍋知宏

ペインクリニック (真興交易)  41 ( 3 ) 377 - 384 2020.03

Research paper (other academic), Single Work

高校生エリート陸上選手におけるサプリメント使用状況

酒井健介, 須永美歌子, 貴島孝太, 森丘保典, 真鍋知宏, 山本宏明, 杉田正明

陸上競技研究紀要 (公益財団法人日本陸上競技連盟)  15   81 - 93 2020.03

Research paper (other academic), Joint Work, Accepted

突然死　アスリートの突然死

真鍋 知宏

日本臨床　別冊循環器症候群III    480 - 484 2019.11

Research paper (scientific journal), Single Work

スポーツ現場における医療行為の法的問題　医師がスポーツ現場で医行為を行う際に準備すべきことと知っておくべきこと

大槻 穣治, 藤谷 博人, 真鍋 知宏, 小松孝行, 山澤 文裕, 武者 春樹

日本臨床スポーツ医学会誌 27 ( 3 ) 388 - 390 2019.08

Research paper (scientific journal), Joint Work

スポーツ現場における医療行為の法的問題　スポーツ現場における医師の医療行為の現状

藤谷 博人, 大槻 穣治, 真鍋 知宏, 小松孝行, 山澤 文裕, 武者 春樹

日本臨床スポーツ医学会誌 27 ( 3 ) 399 - 401 2019.08

Research paper (scientific journal), Joint Work

中高齢者における循環器障害とスポーツ

Manabe Tomohiro

臨床スポーツ医学 35 ( 9 ) 932 - 937 2018.09

Single Work

陸上競技と心臓

Manabe Tomohiro

臨床スポーツ医学 35 ( 6 ) 608 - 614 2018.06

Joint Work