研究者詳細 - 北　洋輔

論文 - 北　洋輔

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オンライン授業に関する教員の認識と姿勢－教員向けアンケート調査に基づいて－

北洋輔, 安田晶子, Gherghel Claudia

Mori Arinori Institute for Higher Education and Global Mobility Working Paper Series No.WP2021-01 1 - 34 2021年05月

筆頭著者, 責任著者

大学入学者選抜が学業成績に与える影響：入試得点および入試区分に着目した分析

Gherghel Claudia, 安田晶子, 北洋輔

Mori Arinori Institute for Higher Education and Global Mobility Working Paper Series No.WP2020-02 1 - 2 2021年03月

最終著者, 責任著者

Assessment and diagnosis of developmental dyslexia in Japanese-English bilingual children A case series study

Okumura Y., Kaga Y., Inagaki M., Kita Y.

No To Hattatsu （No To Hattatsu） 53 （ 2 ） 111 - 117 2021年

ISSN 00290831

Objective: Reading and writing difficulties in children with a multilingual background are often considered to be a consequence of limited language proficiency rather than developmental dyslexia (DD) or intellectual disabilities. However, since these latter conditions are also prevalent in a multilingual population, the present study explored the assessment and diagnosis of DD. through a case-series study of Japa-nese-English bilingual children. Methods: The participants were four school-aged Japanese-English bilingual children (Cases 1-4) with reading and writing difficulties as a major complaint. They were tested for cognitive abilities (IQ) and both oral language and basic literacy skills in Japanese and English, and we made a diagnosis of a specific learning disorder based on DSM-5. Results: Full-scale IQ and oral language abilities in both Japanese and English were within the normal range for all cases. Regarding basic literacy skills, three of them (' nr 1, 3, 4) showed difficulties from the level of Hiragana reading while one (Case 2) showed difficulties in kanji. Two children who used English at school also showed severe difficulties in alphabet naming (Case 3) and oral text reading (Cases 3, 4). Based on these res«,us, Cases 1, 3, and 4 were diagnosed as having a specific learning disorder in both reading and writing, while Case 2 was diagnosed as ha + disorder mainly in writing. Conclusions: The evaluation of basic literacy skills (e. g., letter, word, and simple text reading) were shown to be particularly useful for assessing DD in multilingual children. While assessment and diagnosis in similar cases that involve multipl-guages pose many challenges in practice, approaches that can be used to identify innate specific learning disorders despite the complex environmental and linguistic background are needed.

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Psychological Status Associated With Low Quality of Life in School-Age Children With Neurodevelopmental Disorders During COVID-19 Stay-At-Home Period

Ueda R., Okada T., Kita Y., Ozawa Y., Inoue H., Shioda M., Kono Y., Kono C., Nakamura Y., Amemiya K., Ito A., Sugiura N., Matsuoka Y., Kaiga C., Kubota M., Ozawa H.

Frontiers in Psychiatry （Frontiers in Psychiatry） 12 676493 - 676493 2021年

査読有り

Background: This study seeks to ascertain how the COVID-19 stay-at-home period has affected the quality of life (QOL) of children with neurodevelopmental disorders (NDDs) who had experienced sleep schedules alteration and clarify what psychological status predicted low QOL in children with and without altered sleep patterns. Materials and Methods: Study participants were 86 children between 8 and 17 years of age (mean age, 11.7 years; 70 boys, 16 girls; mean intellectual quotient, 83.6). QOL was evaluated using the self-assessment KINDLR. Participants answered questions regarding depression and anxiety on a visual analog scale (VAS) for temporary mood. Their parents answered questionnaires regarding their maladaptive behaviors and differences in sleep patterns before and during the COVID-19 pandemic. The student's t-test was performed to examine the presence or absence of sleep changes in the children, which affected QOL, temporary mood, and maladaptive behaviors. Multiple or simple linear regression analyses were also performed to identify the psychogenic factors that significantly affected decreased QOL for each group with and without changes in sleep schedule. Results: During the COVID-19 stay-at-home period, 46.5% of participants experienced changes in sleep patterns. These changes were associated with decreased QOL as well as internalized symptoms. The decreased QOL of children with sleep patterns changed was predicted by a high level of depression. In addition, low QOL in children with unchanged sleep patterns was predicted by a high level of depression and low current mood status. Conclusions: Almost half of the participants experienced a poor sleep schedule during the stay-at-home period. These alterations in sleep patterns were associated with a low QOL. The QOL of children with a stable life schedule was affected not only by depressive tendencies but also temporary moods. Therefore, they need to live a fulfilling life to maintain their QOL. However, the QOL of children with poor sleep patterns was affected only by depressive tendencies. Hence, clinicians need to ensure that children with NDDs are well-diagnosed with depression and treated for sleep problems.

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Improvement of brain function after surgery in infants with posterior quadrant cortical dysplasia

Ueda R., Iwasaki M., Kita Y., Takeichi H., Saito T., Nakagawa E., Sugai K., Okada T., Sasaki M.

Clinical Neurophysiology （Clinical Neurophysiology） in press （ 2 ） 332 - 337 2021年

査読有り, ISSN 13882457

Objective: To reveal whether neurodevelopmental outcome of infants after epilepsy surgery can be quantitatively assessed by electroencephalography (EEG) functional connectivity analysis. Methods: We enrolled 13 infants with posterior quadrant dysplasia aged <2 years who were treated using posterior quadrantectomy and 21 age-matched infants. EEG was performed both before and one year after surgery. Developmental quotient (DQ) was assessed both before and 3 years after surgery. The phase lag index (PLI) of three different pairs of electrodes in the nonsurgical hemisphere, i.e., the anterior short distance (ASD), posterior short distance (PSD), and long distance (LD) pairs, were calculated as indices of brain connectivity. The relationship between the PLI and DQ was evaluated. Results: Overall, 77% infants experienced seizure freedom after surgery. The beta- and gamma- range PLI of PSD pairs increased preoperatively. All these pairs normalized postoperatively. Simple linear regression analysis revealed a significant relationship between the postoperative DQ and the postoperative beta-band PLI of ASD pairs. Conclusion: Preoperative abnormal hyper-connectivity was normalized to the control level after surgery. The postoperative hyperconnectivity was associated with long-term neurodevelopmental improvement. Significance: PLI quantifies neurodevelopmental improvements after posterior quadrantectomy.

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Utilizing the self-assessment of school life to find children's concerns

Ozawa H., Kita Y.

No To Hattatsu （No To Hattatsu） 53 （ 1 ） 63 - 65 2021年

ISSN 00290831

We examined the usefulness of the self-assessment of school life for children who have difficulty verbalizing their concerns. Eighty-six students were asked to answer their "concerns about their school life by using open questions and self-assessment of school life. Compared to open questions, there were significantly more children who were able to verbalize their concerns by the self-assessment of school life, and it was considered that the verbalization of concerns was promoted by the quantification process of their own school life.

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学校生活における「困った気持ち」をみつけるための学校自己採点法の活用

小沢浩, 北洋輔

脳と発達 in press 2021年

最終著者, 査読有り

多言語環境児における発達性ディスレクシアの評価と診断:日本語−英語バイリンガル症例のケースシリーズ研究

奥村安寿子, 加賀佳美, 稲垣真澄, 北洋輔

脳と発達（(一社)日本小児神経学会） in press （ 2 ） 111 - 117 2021年

査読有り, ISSN 0029-0831

【目的】多言語環境にある小児の読み書き困難は、学習機会の少なさといった環境要因が原因とされやすいが、発達性読み書き障害や知的能力障害などに基づく場合もある。本研究では、日本語-英語のバイリンガル症例に両言語による基礎的な読み書き評価を適用し、多言語環境児における発達性読み書き障害の評価・診断のあり方を検討した。【方法】読み書きの困難を主訴として医療機関を受診した、日本語-英語バイリンガル児4名に標準化知能検査、英語の口頭言語能力評価、および両言語の基礎的な読み書き検査を実施し、DSM-5による限局性学習症の読字・書字表出困難の診断を行った。【結果】全般的な知的発達水準と口頭言語能力は、全例で正常範囲内にあった。日本語の読み書き検査では、症例1、3、4がひらがな読字から、症例2が漢字で困難を示した。学校言語が英語の2名では、アルファベットの呼称(症例3)と英語の文章音読(症例3、4)にも重篤な困難が認められた。これらより、症例1、3、4は読字および書字表出、症例2は書字表出に特異的な困難がある発達性読み書き障害と診断された。【結論】文字や単語の基礎的な読み書き検査は、多言語環境児の診断的評価に有用であった。複数言語での評価は実施面の課題が多いが、中核症状である正確性・流暢性低下、および言語歴や学習時間等との乖離の把握により、環境要因では説明しがたい生得的な限局性学習症を特定できる。(著者抄録)

Selection of screening items for stuttering: A preliminary study

Yuki Hara, Mari Higashikawa, Wakana Hata, Yuri Sasaki, Takeshi Murakami, Yoko Mizuto, Yosuke Kita, Ikuyo Ishizaka

The Kitasato Medical Journal 2020年10月

査読有り

Adaptive behavior and its related factors in children with focal epilepsy.

Riyo Ueda, Yoshimi Kaga, Yosuke Kita, Masaki Iwasaki, Eri Takeshita, Yuko Shimizu-Motohashi, Akihiko Ishiyama, Takashi Saito, Eiji Nakagawa, Kenji Sugai, Masayuki Sasaki, Masumi Inagaki

Epilepsy & behavior : E&B 108 107092 - 107092 2020年07月

査読有り

OBJECTIVE: We aimed to clarify the strengths and weaknesses in adaptive behavior in children with focal epilepsy and show children-associated factors related to adaptive behavior. MATERIALS AND METHODS: Sixty-three children with focal epilepsy aged 5-18 years with intellectual quotient (IQ) ranging from 67 to 135 were enrolled in this study. Adaptive behavior was evaluated using the Vineland Adaptive Behavior Scale, 2nd edition (VABS-II). The children performed continuous performance test and tests of reading, writing, and IQ; parents answered questionnaires regarding attention-deficit hyperactivity disorder and autism spectrum disorder (ASD). Participants were categorized into four groups based on IQ and adaptive behavior scores for statistical comparisons. RESULTS AND DISCUSSION: Children with low adaptive behavior were more likely to show a reduction in daily living skills, and those with both low adaptive behavior and IQ were more likely to show a reduction in daily living skills and communication. Lower adaptive behavior was related to more severe autistic symptoms, lower academic achievement in children with IQ > 85, and lower executive function in children with IQ ≤ 85. There was a qualitative difference of cognitive dysfunction in adaptive behavior between both groups. CONCLUSIONS: There were differences in VABS-II domain and subdomain characteristics between children with focal epilepsy and those with ASD; however, it was more difficult for children with more severe ASD and coexisting focal epilepsy to show age-equivalent adaptive behavior.

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Executive dysfunction in medication-naïve children with ADHD: A multi-modal fNIRS and EEG study

Yoshimi Kaga, Riyo Ueda, Miho Tanaka, Yosuke Kita, Kota Suzuki, Yasuko Okumura, Yuka Egashira, Yuka Shirakawa, Shota Mitsuhashi, Yuzuki Kitamura, Eiji Nakagawa, Yushiro Yamashita, Masumi Inagaki

Brain and Development （Elsevier BV） 42 （ 8 ） 555 - 563 2020年06月

査読有り, ISSN 0387-7604

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生後３〜４か月の睡眠リズムの確立と自閉スペクトラム症

星野恭子, 長尾ゆり, 木村一恵, 林雅晴, 北洋輔

日本小児科学会雑誌 124 （ 5 ） 819 - 824 2020年05月

査読有り

Reduced Nogo-P3 in adults with developmental coordination disorder (DCD).

Kota Suzuki, Yosuke Kita, Yuka Shirakawa, Yuka Egashira, Shota Mitsuhashi, Yuzuki Kitamura, Hideyuki Okuzumi, Yoshimi Kaga, Masumi Inagaki

International journal of psychophysiology : official journal of the International Organization of Psychophysiology 153 37 - 44 2020年04月

査読有り

Nogo-N2 is associated with the premotor cognitive process that precedes motor response (e.g., conflict monitoring), whereas Nogo-P3 is related to the inhibition of the actual motor response. We examined the influence of motor clumsiness of developmental coordination disorder (DCD) on components of the event-related potential in a Go/Nogo task. Participants were healthy adults (N = 81) that were classified into control and DCD groups based on the Movement Assessment Battery for Children Second Edition. We manipulated the difficulty in stopping a response by varying the frequency of Nogo stimuli in a response task into rare (20%) and frequent (80%) conditions, and Nogo-N2 and Nogo-P3 were calculated from electroencephalograms (EEGs) during the Go/Nogo tasks. The commission error rate in the rare condition was significantly higher in the DCD group than in the control group, indicating that motor clumsiness decreases task performance. There were no differences in Nogo-N2 between DCD and control groups. However, Nogo-P3 in the rare condition was reduced in the DCD group compared to the control group. These results suggest that the influence of motor clumsiness is limited to the cognitive process after the initiation of the actual motor response.

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Discrepancy between musical ability and language skills in children with Williams syndrome.

Yuzuki Kitamura, Yosuke Kita, Yasuko Okumura, Yoshimi Kaga, Hideyuki Okuzumi, Yuji Ishikawa, Miho Nakamura, Masumi Inagaki

Brain & development 42 （ 3 ） 248 - 255 2020年01月

査読有り

BACKGROUND: Children with Williams syndrome (WS) show a marked interest in music, a characteristic often explored in clinical settings. However, the actual musical abilities of patients with WS remain debatable due to some of the relevant data being derived from experimental tasks that require a verbal response, despite the known language impairments in WS. The present study aimed to examine musical ability in children with WS using a newly invented pitch discrimination task with minimal involvement of language and clarify its relationship with language skill. METHODS: Eleven children with WS participated in the study. We used a novel pitch discrimination task that required minimal language use. Two piano tones were presented sequentially, and children were asked to give a non-verbal response as to whether the second tone was higher than, lower than, or the same as the first tone. RESULTS: Pitch discrimination performance in children with WS was lower than the level predicted for their chronological age (CA), even in the non-verbal task. Pitch discrimination ability and verbal mental age (VMA) were shown to be dissociated, such that children with WS with a lower skill level for language showed an unexpectedly higher level of pitch discrimination ability and vice versa. CONCLUSIONS: Our results indicated reduced musical ability with respect to CA in children with WS. The dissociation between musical ability and language skills may indicate unique developmental relationships that differ from those in normal children. These findings provide new evidence to support the importance of assessing actual musical ability in WS prior to implementing interventional music therapy.

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Postoperative improvement of executive function and adaptive behavior in children with intractable epilepsy

Ueda R., Kaga Y., Kita Y., Tanaka M., Iwasaki M., Takeshita E., Shimizu-Motohashi Y., Ishiyama A., Saito T., Nakagawa E., Sugai K., Sasaki M., Okada T., Inagaki M.

Brain and Development （Brain and Development） 43 （ 2 ） 280 - 287 2020年

ISSN 0387-7604

Introduction: An alteration in postoperative cognitive function varies according to the patients’ background characteristics, such as etiology, focus, and seizure duration. Accurate prediction and assessment of postoperative cognitive function is difficult in each patient. Adaptive behavior could describe the typical performance of daily activities and represents the ability to translate cognitive potential into real-world skills. We examined the relationship between alterations of executive function (EF) and adaptive behavior in school children undergoing surgery for intractable epilepsy. Methodology: We enrolled 31 children with focal resection or corpus callosotomy for intractable epilepsy [mean age at surgery, 12.5 years; 16 boys; mean intellectual quotient, 73.3]. We surveyed answered questionnaires on attention-deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and adaptive behavior using the Vineland Adaptive Behavior Scale, 2nd edition (VABS-II), and performed continuous performance tests (CPTs) on children pre- and postoperatively. Result: ADHD and ASD symptoms improved after epilepsy surgery. The omission error (OE) in the CPT variable improved after epilepsy surgery, especially in children with a shorter preoperative period. Improved ASD symptoms led to an increased score of the coping skills subdomain. The reduced OE observed after surgery also increased the score of the community skills subdomain. Conclusion: Improvement in EF and ASD symptoms resulted in better adaptive behavior postoperatively. These results were important for the pre- and postoperative evaluation and re-evaluation of children with epilepsy requiring special education and related services.

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注意欠如多動症児の協調運動機能が行為選択に及ぼす影響

北洋輔, 白川由佳, 鈴木浩太, 江頭優佳, 加賀佳美, 北村柚葵, 西村悠貴, 山下裕史朗, 稲垣真澄

脳と発達（一般社団法人日本小児神経学会） 52 （ 1 ） 5 - 10 2020年

査読有り, ISSN 0029-0831

<p> 【目的】注意欠如多動症 (attention deficit hyperactivity disorder ; ADHD) 児の外傷予防に向けて, ADHD児の協調運動機能を調べるとともに, それらが環境下での行為選択に与える影響を検討した. 【方法】ADHD児35名と定型発達児51名とした比較対照実験を行った. 各児の協調運動機能をThe Movement Assessment Battery for Children Second Editionによって評価した. また, 高さが可変する水平ロープを通り抜ける際に, 「またぐ」か「くぐる」かの行為を選ぶ実験課題を通して, 環境下での行為選択を評価した. それぞれの成績について群間比較を行うとともに, 行為選択に与える要因を検討した. 【結果】定型発達児に比して, ADHD児は, 協調運動機能が低く, 特にボール運動・バランスが低成績であった. 行為選択課題では, ADHD児はロープが低い位置にあるにもかかわらず, くぐろうとする行為が多くみられた. これらの行為選択には, 協調運動機能の影響は少なく, 注意機能の影響が強く認められた. 【結論】本邦のADHD児では粗大運動や道具を使用した運動に困難さが認められた. 彼らの非効率な行為選択には, 環境や身体図式に注意を向ける弱さが影響しており, 外傷予防には運動機能に加えて, 注意機能への配慮が必要と示唆された. </p>

漢字熟語の逸脱検出時の脳磁場反応

江頭優佳, 加賀佳美, 軍司敦子, 北洋輔, 木村元洋, 廣永成人, 金子裕, 高橋秀俊, 花川隆, 稲垣真澄

日本生体磁気学会誌（日本生体磁気学会） 33 （ 1 ） 164 - 166 2020年

ISSN 0915-0374

就学前の発達性協調運動障害(DCD)早期発見のためのチェックリストと活用マニュアルの完成顕在化しにくい発達障害を早期に抽出するアセスメントツールの開発研究から

斉藤まなぶ, 北洋輔, 大里絢子, 三上美咲, 小枝周平, 三上珠希, 稲垣真澄, 中村和彦

日本児童青年精神医学会総会抄録集（(一社)日本児童青年精神医学会） 60回 P14 - 3 2019年12月

査読有り

Prevalence estimates of neurodevelopmental disorders in Japan: A community sample questionnaire study.

Kita Y, Ashizawa F, Inagaki M

Psychiatry and clinical neurosciences in press 2019年10月

査読有り, ISSN 1323-1316

AIM: Prevalence estimates of neurodevelopmental disorders have been calculated by questionnaire surveys scored by a single rater, which introduces inherent rater biases. The present study aimed to estimate the prevalence and comorbidity rates of four neurodevelopmental disorders based on both parent and teacher rating scales. METHODS: We performed a community sample survey recruiting 3852 children aged 6 to 9 years. Parents and teachers evaluated clinical conditions in children using questionnaire-style scales. These scales with cut-off values were used to estimate the prevalence and comorbidity rates of attention deficit hyperactive disorder, autism spectrum disorder, specific learning disorder (or developmental dyslexia), and developmental coordination disorder. RESULTS: The prevalence estimates were separately confirmed according to the raters. Some estimates were higher than those in previous studies conducted in other countries. We also found a large disagreement between the parent and teacher rating scores. Moreover, the degree of agreement between two raters varied depending on the severity of the child's clinical condition. CONCLUSION: These estimates are the first findings based on evaluating children by two different raters. The prevalence and comorbidity estimates are informative for researchers and clinicians of pediatric neurology. The disagreements between two different raters raise questions about previous estimates of neurodevelopmental disorders.

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運動の不器用さが反応抑制に関わる事象関連電位成分に及ぼす影響

鈴木浩太, 北洋輔, 白川由佳, 江頭優佳, 加賀佳美, 北村柚葵, 三橋翔太, 新垣香菜, 奥住秀之, 稲垣真澄

日本心理学会大会発表論文集（公益社団法人日本心理学会） 83 2A-050 - 2A-050 2019年09月

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