論文 - 北　洋輔

Applicability of the Movement Assessment Battery for Children-Second Edition to Japanese children: A study of the Age Band 2

Yosuke Kita, Kota Suzuki, Shogo Hirata, Kotoe Sakihara, Masumi Inagaki, Akio Nakai

BRAIN & DEVELOPMENT （ELSEVIER SCIENCE BV）  38 （ 8 ） 706 - 713 2016年09月

査読有り,  ISSN  0387-7604

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Background: The diagnosis of Developmental Coordination Disorder (DCD) requires a precise assessment of motor skills via a standardized tool such as the Movement Assessment Battery for Children-Second Edition (MABC-2). Although the MABC-2 has been widely used in English-speaking countries, to the best of our knowledge, no studies have examined its applicability to Japanese children. Thus, it has been difficult to diagnose DCD in Japan.
Aims: As a preliminary investigation preceding its formal standardization in Japan, we examined the applicability of the MABC-2.
Methods and procedures: Participants comprised 132 typically developing Japanese children who completed a test set of the MABC-2 for Age Band 2. We analyzed both internal consistency and factorial validity for our Japanese sample. We also included a comparison between our sample of Japanese children and the normative sample of the MABC-2, as well as an examination of gender differences.
Outcomes and results: Our results indicated acceptable internal consistency and scale homogeneity. High factorial validity, which has not been examined in other populations, was also confirmed for the test set. Moreover, we found differences in component scores between the Japanese and normative children with respect to Manual Dexterity and Balance. We also found that girls obtained superior Manual Dexterity and Balance scores compared with boys.
Conclusions and Implications: The present findings represent the first step towards the standardization of the MABC-2 in a Japanese population. (C) 2016 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

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The Association between Children's Behavior and Parenting of Caregivers: A Longitudinal Study in Japan.

Suzuki K, Kita Y, Kaga M, Takehara K, Misago C, Inagaki M

Frontiers in public health （FRONTIERS MEDIA SA）  4   17 2016年02月

査読有り,  ISSN  2296-2565

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The purpose of this study was to elucidate the association between children's behavior (i.e., prosocial and problematic behavior) and the parenting style (i.e., laxness and overreactivity) of their caregivers by using longitudinal data in the Japanese population. These data were collected when the children were 7.5 and 9 years. We proposed three hypotheses: children's behavior at 7.5 years will predict their behavior at 9 years; children's behavior at 7.5 years will predict the parenting of their caregivers; and the parenting style of caregivers will affect their children's behavior at 9 years. We evaluated children's behavior and parenting behavior using a strength and difficulties questionnaire and a parenting scale. The hypotheses were tested using structural equation modeling (SEM). The results of the SEM showed that children's behavior at 7.5 years predicted their behavior at 9 years. Children's problematic behavior at 7.5 years triggered over-reactive parenting in their caregivers at 9 years, which increased problematic behavior and decreased prosocial behavior in the children at 9 years. These findings indicate the association between children's behavior and the parenting style of caregivers in Japan.

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ADHD児におけるニューロフィードバック療法の効果予測

奥村 安寿子, 北 洋輔, 大森 幹真, 鈴木 浩太, 福田 亜矢子, 安村 明, 稲垣 真澄

認知神経科学 （認知神経科学会）  18 （ 2 ） 86_2 - 86_2 2016年

ISSN  1344-4298

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Down症児の粗大運動発達力が摂食嚥下機能の発達に与える影響

中村 達也, 鮎澤 浩一, 北 洋輔, 甲斐 智子, 小沢 浩

言語聴覚研究 （日本言語聴覚士協会 ; 2004-）  13 （ 1 ） 3 - 10 2016年

査読有り,  ISSN  1349-5828

ADHD児の空間性ワーキングメモリにかかわる脳血流動態の特徴

大井 雄平, 北 洋輔, 鈴木 浩太, 奥村 安寿子, 奥住 秀之, 山下 裕史朗, 稲垣 真澄

認知神経科学 （認知神経科学会）  18 （ 2 ） 93_2 - 93_2 2016年

ISSN  1344-4298

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学習障害の成人期までの経過と治療の考え方 (特集 出口を見据えた精神医療 : 何処をめざし如何に診るか)

北 洋輔, 稲垣 真澄

精神保健研究 = Journal of mental health : official journal of the National Institute of Mental Health, NCNP, Japan （国立精神・神経医療研究センター精神保健研究所）   （ 29 ） 73 - 80 2016年

査読有り,  ISSN  0915-065X

視覚誘発電位を用いた緑内障・高眼圧症の大細胞系機能評価

山崎 広子, 北 洋輔, 小林 朋佳, 加我 牧子, 稲垣 真澄

臨床神経生理学 （一般社団法人 日本臨床神経生理学会）  44 （ 1 ） 11 - 19 2016年

査読有り

　概要を見る

<p>緑内障・高眼圧症の大細胞系機能の他覚的評価のため低空間周波数, 高時間周波数, 低コントラストの視覚刺激 (M刺激) を新たに作成し, pattern reversal条件でVEPを記録した。緑内障例8名, 高眼圧症例5名, 健常対照13名のOz部VEP波形をComplex demodulation法により解析しpeak振幅を求めた。疾患群のVEP peak振幅値はコントラスト10%と15%で有意に低下した。コントラストの対数値対peak振幅のプロットに基づく回帰直線から算出したコントラスト閾値は疾患群で有意に高値を示した (<i>p</i><0.05) 。疾患群の13眼中6眼において, コントラスト閾値が健常群の平均+2SDの値 (4.49%) を超えていた。以上からM刺激によるVEP検査は, 緑内障・高眼圧症症例の網膜から第一次視覚野までの大細胞系機能障害を早期に, 他覚的かつ定量的に捉えうることが示された。</p>

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Lateralized frontal activity for Japanese phonological processing during child development

Takaaki Goto, Yosuke Kita, Kota Suzuki, Toshihide Koike, Masumi Inagaki

FRONTIERS IN HUMAN NEUROSCIENCE （FRONTIERS MEDIA SA）  9   417 2015年07月

査読有り,  ISSN  1662-5161

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Phonological awareness is essential for reading, and is common to all language systems, including alphabetic languages and Japanese. This cognitive factor develops during childhood, and is thought to be associated with shifts in brain activity. However, the nature of this neurobiological developmental shift is unclear for speakers of Japanese, which is not an alphabetical language. The present study aimed to reveal a shift in brain functions for processing phonological information in native-born Japanese children. We conducted a phonological awareness task and examined hemodynamic activity in 103 children aged 7-12 years. While younger children made mistakes and needed more time to sort phonological information in reverse order, older children completed the task quickly and accurately. Additionally, younger children exhibited increased activity in the bilateral dorsolateral prefrontal cortex (DLPFC), which may be evidence of immature phonological processing skills. Older children exhibited dominant activity in the left compared with the right DLPFC, suggesting that they had already acquired phonological processing skills. We also found significant effects of age and lateralized activity on behavioral performance. During earlier stages of development, the degree of left lateralization appears to have a smaller effect on behavioral performance. Conversely, in later stages of development, the degree of left lateralization appears to have a stronger influence on behavioral performance. These initial findings regarding a neurobiological developmental shift in Japanese speakers suggest that common brain regions play a critical role in the development of phonological processing skills among different languages systems, such as Japanese and alphabetical languages.

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自閉症スペクトラム障害児の不器用さに対する認知指向型・家族参加型グループリハビリテーションの試み : しまはちチャレンジグループの有効性と課題

多辺田 俊平, 相崎 貢一, 北 洋輔

作業療法 = Japanese occupationai therapy researh : JOTR （日本作業療法士協会 ; 1982-）  34 （ 3 ） 307 - 316 2015年06月

査読有り,  ISSN  0289-4920

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[Brain functions in developmental dyslexia].

Kita Y

No to hattatsu. Brain and development 47 （ 3 ） 194 - 197 2015年05月

査読有り,  ISSN  0029-0831

A preliminary study of the Movement Assessment Battery for Children-Second Edition on Japanese children: Age band 1

Suzuki K, Hirata S, Kita Y, Sakihara K, Inagaki M, Nakai A

Journal of Comorbidity 5   101 2015年

査読有り

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A preliminary study of the Movement Assessment Battery for Children-Second Edition on Japanese children: Age Band 2

Kita Y, Hirata S, Suzuki K, Sakihara K, Inagaki M, Nakai A

Journal of Comorbidity 5   86 2015年

査読有り

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Longitudinal change in motor skills in children with autism spectrum disorders

Hirata S, Kita Y, Suzuki K, Okuzumi H, Kokubun M, Nakai A

Journal of Comorbidity 5   83 2015年

査読有り

脳機能における特徴

北 洋輔

脳と発達 （The Japanese Society of Child Neurology）  47 （ 3 ） 194 - 197 2015年

査読有り,  ISSN  0029-0831

　概要を見る

発達性ディスレクシア (developmental dyslexia ; DD) に関する脳機能研究について概観した. 脳機能研究は, 文字の読みそのものに関わる脳機能の検討と, 読みを支える認知的要因の検討の二つに大別され, 後者はDDの病態解明を目指すアプローチとされる. 我々は後者に着目し, 日本語話者のDDの病態解明に取り組んでいる. 音韻処理に関わる脳機能研究からは, 大脳基底核など日本語独自の病態が示唆される一方, 大細胞系視知覚に関わる研究からは, アルファベット語圏と共通する病態の存在も見出された. これらから, 日本語話者のDDの病態にいくつかのサブタイプが存在することが示唆されるとともに, 今後はサブタイプに応じた適切な治療や教育の選択が期待される.

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視覚誘発電位を用いた大細胞系機能評価と読字能力の関連性

小林朋佳, 稲垣真澄, 山崎広子, 北洋輔, 加我牧子, 岡明

脳と発達 46   424 - 428 2015年

査読有り

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Differential electrophysiological responses to biological motion in children and adults with and without autism spectrum disorders

Masahiro Hirai, Atsuko Gunji, Yuki Inoue, Yosuke Kita, Takashi Hayashi, Kengo Nishimaki, Miho Nakamura, Ryusuke Kakigi, Masumi Inagaki

RESEARCH IN AUTISM SPECTRUM DISORDERS （ELSEVIER SCI LTD）  8 （ 12 ） 1623 - 1634 2014年12月

査読有り,  ISSN  1750-9467

　概要を見る

Although atypical processing of biological motion (BM) in individuals with autism spectrum disorder (ASD) has been reported, the temporal profile of the neural response to BM is not well explored. In the current study, event-related potentials (ERPs) were measured in 12 individuals with ASD, aged 8-22 years, and 12 age- and gender-matched normal controls, to investigate the electrophysiological response to BM and a control visual stimulus. By introducing a novel experimental paradigm that can dissociate the electrophysiological responses to motion processing and the global shape processing of BM, we found that: (1) the timing of the response was preserved in ASD groups, whereas (2) the ERP response to BM was significantly enhanced compared with scrambled point-light motion (SM) in normal controls; the responses to both BM and SM were not significantly different in subjects with ASD. Because we did not find a significant group effect on the peak and mean amplitude induced by BM, it is presumed that this atypical response in individuals with ASD was due to over-sensitivity to the local motion signals. This experimental paradigm showed atypical local motion processing of BM in individuals with ASD. (C) 2014 Elsevier Ltd. All rights reserved.

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Relationship between magnocellular function and reading skills in children: A study using visual evoked potentials

Tomoka Kobayashi, Masumi Inagaki, Hiroko Yamazaki, Yosuke Kita, Makiko Kaga, Akira Oka

No To Hattatsu （Japanese Society of Child Neurology）  46 （ 6 ） 424 - 428 2014年11月

査読有り,  ISSN  0029-0831

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Objective: Developmental dyslexia (DD) is a neurodevelopmental disorder that is characterized by difficulties with accurate and/or fluent word recognition and by poor spelling and decoding abilities. The magnocellular deficit theory is one of several hypotheses that have been proposed to explain the pathophysiology of DD. In this study, we investigated magnocellular system dysfunction in Japanese dyslexic children.
Methods: Subjects were 19 dyslexic children (DD group) and 19 aged-matched healthy children (TD group). They were aged between 7 and 16 years. Reversed patterns of black and white sinusoidal gratings generated at a low spatial frequency, high reversal frequency of 7.5 Hz, and low contrasts were used specifically to stimulate the magnocellular system. We recorded visual evoked potentials (VEP) from the occipital area and examined their relationship with reading and naming tasks, such as the time to read hiragana characters, rapid automatized naming of pictured objects, and phonological manipulation.
Results: Compared to the TD group, the DD group showed a significantly lower peak amplitude of VEPs through the complex demodulation method. Structural equation modeling showed that VEP peak amplitudes were related to the rapid automatized naming of pictured objects, and better rapid automatized naming resulted in higher reading skills. There was no correlation between VEP findings and the capacity for phonological manipulation.
Conclusions: VEPs in response to the magnocellular system are useful for understanding the pathophysiology of DD. Single phonological deficit may not be sufficient to cause DD.

Face recognition in children with autism spectrum disorders

Yosuke Kita

INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY （ELSEVIER SCIENCE BV）  94 （ 2 ） 141 - 142 2014年11月

査読有り,  ISSN  0167-8760

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Psychometric properties of Japanese version of the Swanson, Nolan, and Pelham, version-IV Scale-Teacher Form: A study of school children in community samples

Yuki Inoue, Keiko Ito, Yosuke Kita, Masumi Inagaki, Makiko Kaga, James M. Swanson

BRAIN & DEVELOPMENT （ELSEVIER SCIENCE BV）  36 （ 8 ） 700 - 706 2014年09月

査読有り,  ISSN  0387-7604

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Background: Psychometric properties of The Japanese version of Swanson, Nolan, and Pelham IV scale (SNAP-IV)-Teacher Form were examined in this study. Method: Community samples of 1296 children (Grade 1-9, boys 52.9%) were collected from public elementary/middle schools in suburban areas. Teachers rated their children's behavior using Japanese version of SNAP-IV-Teacher Form and Strength and Difficulties Questionnaire (SDQ). Results: A three-factor structure model, which was equivalent with AD/HD symptoms subscales (inattention, hyperactivity/impulsivity) and oppositional-defiant disorder symptoms subscale was obtained and confirmed in an explorative/confirmative factorial analysis (Goodness-of-Fit Index = 0.913, Comparative Fit Index = 0.959, root mean square error of approximation = 0.056). The current version of the SNAP-IV-Teacher Form demonstrated good test retest reliability (intra-class correlation = 0.752-0.822), high internal consistency (Cronbach's a = 0.933-0.952), significant correlations with relevant subscales of Japanese version of SDQ, and typical effects of age and gender on those subscales. Conclusion: The current study indicates that the Japanese version of SNAP-IV-Teacher Form is a reliable and valid instrument for rating symptoms related to AD/HD and ODD. (C) 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

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特別支援教育における小学校教員と言語聴覚士の連携に関する調査

中村 達也, 鮎澤 浩一, 北 洋輔

言語聴覚研究 （日本言語聴覚士協会 ; 2004-）  11 （ 3 ） 166 - 174 2014年

査読有り,  ISSN  1349-5828

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